Abstract
In the post-salt iodization phase, a study on iodine nutriture status was conducted in Tripura of North East India. The clinical variable of the study was goiter and the biochemical variables were urinary iodine and thiocyanate. Random sampling methodology was followed for selecting the study areas in the State. In each study area, the studied population consisted of school children of both sexes in the age group 6–15 years. The total study areas were 22 and the total number of the population was 10,801. The total number of urine samples were analysed for iodine and thiocyanate were 1,032 (about 10%). The total goiter rate was 21.63%. Population of most of the studied areas had no biochemical iodine deficiency as evidenced by median urinary iodine excretion levels. However, the per capita consumption of iodine of about 40% population was inadequate. A large number of cyanogenic plants (SCN precursors) are used as common vegetables. This study ensures that the existing goiter prevalence in the region could possibly due to non-uniform adequate iodine supply along with the thiocyanate load.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Kochupillai N. Neonatal hypothyroidism in India.Mount Sinai Journal of Medicine 1992; 59(2): 111–115.
Pandav CS, Malik A, Anand K, Pandav S, Karmakar MG. Prevalence of iodine deficiency disorders among school children of the national capital territory of Delhi. ICCIDD, Regional Office of South Asia and Pacific, New Delhi (1996).
Chandra AK, Ray I, Ray P. Studies on the current state of iodine nutrition of the school age children in West Tripura, N.E. India.Ind J Physiol & Allied Sc 1997; 51 (2): 91–100.
Chandra AK, Ray I, Ray P. Iodine nutritional status of the school age children in South Tripura, N.E. India.Ind J Physiol Pharmacol 1997; 41 (3): 263–268.
Chandra AK, Ray I Ray P. Iodine intake, iodine excretion and goiter prevalence in North Tripura, N.E. India.Ind J Nutr Dietet 1999; 36 (7): 339–345.
Indicators for Trackling Progress in IDD elemination.IDD News Letter 1994; 10 (4) : 40.
Stanbury JB, Hetzel B.Endemic Goiter and Endemic Cretinism: Iodine Nutrition in Health and Disease. New York, Wiley & Sons, New York, 1980 :606.
Ermans AM, Mbulamko NB, Delange F, Ahluwalia R. eds.Role of Cassava in the Etiology of Endemic Goiter and Cretinism, IDRC-136, IDRC, Ottawa, 1983:13–166.
Gaitan E, Lindsay RH, Cooksey RC. Antithyroid effectsin vivo andin vitro of vitexin: A C-glucorylflavons in millet.J Clin Endocrinol Metab 1995; 80:1144–1147.
Gaitan E, Nelson NC, Poole GV. Endemic goiter and endemic thyroid disorder.World J Surg 1991; 15: 205–215.
Chandra AK, Ray I, Ray P. Iodine content in water of Tripura in North Eastern India.J Food Sci Technol 1999; 36 (6): 558–560.
Global prevalence of iodine deficiency disorders. Micronutrient Deficiency Information System, WHO, MDIS Working Paper # 1,1993.
Dunn JT, Crutchfield HE, Gutekunst R, Dunn D. Iodine deficiency disorders and urinary iodine level. In (ICCIDD eds). Methods of Measuring Urinary Iodine, Netherlands 1993; 1:15.
“Indicators for Assessing Iodine Deficiency Disorders Report of the Joint WHO/UNICEF/ICCIDD Consultation on IDD Indicators, Geneva, November 1992”. WHO/NUT/93.1, September, 1993.
Karmakar MG, Pandav CS and Krishnamachari KAVR.Principle and Procedure of Iodine Estimation. A Laboratory Manual, Indian Council of Medical Research, New Delhi, 1986.
Aldridge WN. The estimation of microquantities of cyanide and thiocyanate.Analyst (London) 1945; 70: 474–475.
Michajlovskiji N, Langer P. Studien uber Beziehungen zwischen Rhodanbildung und Kropfbildender Eigenschaft von Nahrungsmitteln. I: Gehalt einiger Nahrungs mittel and praformierten Rhodanid.Z Physiol Chem 1958; 312 :26–30.
Stanbury JB, Pinchera A. Measurement of iodine deficiency disorders. In. Hetzel BS, Pandav CS, eds.SOS for a Billion: The Conquest of Iodine Deficiency Disorders; Delhi, Oxford University Press, 1994: 73–88.
Delange F, Bourdoux P, Colinet Eet al. Nutritional factors involved in the goitrogenic action of cassava. In Delange F and Ahluwalia R, eds.Cassava Toxicity and Thyroid Research and Public Health Issues IDRC-207e, Ottawa, 1983; 17–26.
Delange F, Iteke FB and Ermans AM. Nutritional factors involved in the goitrogenic action of cassava, IDRC-184e, Ottawa, 1982.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Chandra, A.K., Ray, I. Dietary supplies of iodine and thiocyanate in the etiology of endemic goiter in Tripura. Indian J Pediatr 68, 399–404 (2001). https://doi.org/10.1007/BF02723011
Issue Date:
DOI: https://doi.org/10.1007/BF02723011