Skip to main content
SpringerLink
Log in

Synthesis, antibacterial and antifungal activity of some derivatives of 2-phenyl-chromen-4-one

  • Full Papers
  • Published:
Journal of Chemical Sciences Aims and scope Submit manuscript

Abstract

Some derivatives of 2-phenyl-chromen-4-one (flavone ring) have been synthesized and tested for antibacterial and antifungal activities along with their chalcone precursors against four human pathogenic bacteria and five plant mould fungi. The structures of the synthesized compounds were elucidated by UV, IR and1H NMR spectroscopic techniques, and elemental analysis. The antibacterial and antifungal screens of the synthesized compounds were performed in vitro by the filter paper disc diffusion method and the poisoned food technique.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Miroslawa K-B and Marian W 2003Z. Naturforsch C58 65

    Google Scholar 

  2. Weidenbörner M and Jha H C C 2003Int. Symp. on Natural phenols in Plant Resistance, Int. Soc. Horticultural Sci. Acta Horticulture, p 381

  3. Tanaka T, Iinuma M, Yuki K, Fujii Y and Mizuno M 1992Phytochemistry 31 993

    CAS  Google Scholar 

  4. Vender Berghe DAR, Haemers A and Vlieunek A J 1993 InBioactive natural products;Detection and structural determination (eds) S M Colegate and K J Molyneux (London: CRC Press) ch. 17, pp 405–440

    Google Scholar 

  5. Bors W, Heller W, Michel C and Saran M 1990 InMethods in enzymology (eds) L Packer and A N Glazer (New York: Academic Press) vol 186, pp 343–355

    Google Scholar 

  6. Alam S, Sarkar Z and Islam A 2004J. Chem. Sci. 116 29

    Article  CAS  Google Scholar 

  7. Alam S, Miah M A J and Islam A 2004J. Biol. Sci. 4 527

    Article  Google Scholar 

  8. Alam S 2004Acta Chim. Slov. 2004 51 (in press)

  9. Alam S, Miah M A J and Islam A 2004ACGC Chem. Res. Commun. 17 (in press)

  10. Doshi A G, Soni P A and Ghiya B J 1986Indian J. Chem. 258 759

    Google Scholar 

  11. Hoshino Y, Ohinata T and Taken N 1986Bull. Chem. Soc. (Jpn) 59 2351

    Article  CAS  Google Scholar 

  12. Mahal H S, Raj H S and Venkataraman K 1935J. Chem. Soc. 1965

  13. Arima H, Ashida H and Danno G-I 2002Biosci. Biotechnol. Biochem. 66 1014

    Google Scholar 

  14. Jeongmok K, Maurice RM and Cheng IW 1995J. Agric. Food Chem. 43 2834

    Google Scholar 

  15. Nishina C, Enoki N, Tawata S, Mori A, Kobayashi K and Fukushima M 1987Agric. Biol. Chem. 51 139

    Google Scholar 

  16. Grover R K and Moore J D 1962Phytopathology 52 876

    CAS  Google Scholar 

  17. Miah MAT, Ahmed H U, Sharma N R, Ali A and Miah S A 1990Bangladesh J. Bot. 19 5

    Google Scholar 

  18. 19. Aneja R, Khanna RN and Sheshadri TR 1963J. Chem. Soc. 163

  19. Talapatra S K, Mallik A K and Talapatra B 1980Phytochemistry 19 1199

    Article  CAS  Google Scholar 

Download references

Author information

Author notes

  1. Sayed Alam

    Present address: Department of Life Science and Biotechnology, Shimane University, Matsue, 690-8504, Shimane, Japan

Authors and Affiliations

  1. Department of Chemistry, Rajshahi University of Engineering and Technology, 6204, Rajshahi, Bangladesh

    Sayed Alam

Authors
  1. Sayed Alam
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Alam, S. Synthesis, antibacterial and antifungal activity of some derivatives of 2-phenyl-chromen-4-one. J Chem Sci 116, 325–331 (2004). https://doi.org/10.1007/BF02711433

Download citation

  • Received:

  • Revised:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02711433

Keywords

Search

Navigation