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Small-angle neutron scattering study of sodium cholate and sodium deoxycholate interacting micelles in aqueous medium

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Abstract

Small angle neutron scattering (SANS) measurements of D2O solutions (0.1 M) of sodium cholate (NaC) and sodium deoxycholate (NaDC) were carried out atT= 298 K. Under compositions very much above the critical micelle concentration (CMC), the bile salt micelle size growths were monitored by adopting Hayter-Penfold type analysis of the scattering data. NaC and NaDC solutions show presence of correlation peaks atQ = 0.12 and 0.1 å-1 respectively. Monodisperse ellipsoids of the micelles produce best fits. For NaC and NaDC systems, aggregation number (9.0, 16.0), fraction of the free counterions per micelle (0.79, 0.62), semi-minor (8.0 å) and semi-major axes (18.4, 31.7 å) values for the micelles were deduced. Extent of micellar growth was studied using ESR correlation time measurements on a suitable probe incorporating NaC and NaDC micelles. The growth parameter (axial ratio) values were found to be 2.3 and 4.0 for NaC and NaDC systems respectively. The values agree with those of SANS.

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Authors and Affiliations

  1. Department of Physical Chemistry, University of Madras, Guindy Campus, 600 025, Chennai, India

    J Santhanalakshmi & G Shantha Lakshmi

  2. Condensed Matter Physics Division, Bhabha Atomic Research Division, Trombay, 400 085, Mumbai, India

    V K Aswal & P S Goyal

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  1. J Santhanalakshmi
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  2. G Shantha Lakshmi
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  3. V K Aswal
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  4. P S Goyal
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Correspondence to J Santhanalakshmi.

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Santhanalakshmi, J., Lakshmi, G.S., Aswal, V.K. et al. Small-angle neutron scattering study of sodium cholate and sodium deoxycholate interacting micelles in aqueous medium. J Chem Sci 113, 55–62 (2001). https://doi.org/10.1007/BF02708552

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  • DOI: https://doi.org/10.1007/BF02708552

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