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Characterization of mitochondrial DNA primase fromSaccharomyces cerevisiae

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Abstract

DNA primase from yeast mitochondria was shown to have a molecular weight of 67 kDa by SDS-PAGE and an S value of 5.5. It was shown to have preference for SS mitochondrial DNA especially fragments containing origins of replication, as a template to initiate DNA replication. Further examination of the enzyme showed its possible association with a ribonucleotide moiety essential for enzyme activity.

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Murthy, V., Pasupathy, K. Characterization of mitochondrial DNA primase fromSaccharomyces cerevisiae . J Biosci 19, 1–8 (1994). https://doi.org/10.1007/BF02703462

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  • DOI: https://doi.org/10.1007/BF02703462

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