Abstract
The acquisition time of common fast imaging techniques is limited by the switching times of the magnetic field gradients necessary to encode the RF signal for the spatial coordinates. We introduce a method by which multiple spin echoes are generated using a burst of short RF pulses. Spatial encoding can be introduced into the echotrain using very few gradient switching steps. Acquisition times as short as 40 ms for a 64 × 128 image matrix can thus be achieved on a whole body system using a conventional gradient system with a gradient amplitude of 10 mT/m and 1 ms switching time. Different possibilities to introduce slice selection into the basically non-slice selective experiment are presented which also allow to manipulate the image contrast. Quantitative measurements of T1- and T2-relaxation rates as well as diffusion and perfusion constants can thus be performed within a few seconds.
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References
Mansfield P (1977) Multi-planar image formation using NMR spin echoes.J Phys C 10: L55-L58.
Pykett IL, Rzedzian LL (1987) Instant images of the body by magnetic resonance.Magn Reson Med 5: 563.
Haase A (1990) Snapshot FLASH MRI. Application to T1, T2 and chemical-shift-imaging.Magn Reson Med 13: 77–89.
Haase A, Frahm J, Matthaei D, Hänicke W, Merboldt KD (1986) FLASH imaging. Rapid NMR imaging using low flip-angle pulses.J Magn Reson 67: 258–266.
Mueri M, Hennig J (1989) Ultrafast MR imaging with the Snapshot-FLARE method.Radiology 173(P): 411.
Norris DG (1991) Ultrafast low-angle RARE: U-FLARE.Magn Reson Med 176: 539–542.
Jones RA, Rinck PA (1991) Snapshot imaging using a FLARE sequence.Magn Reson Med 211: 282–287.
Hennig J, Mueri M (1988) Fast imaging using burst excitation pulses.Proc. VIIth. Ann. Meeting SMRM p. 238.
Hennig J (1991) Echoes — How to generate, recognize, use or avoid them in MR-imaging sequences. Part I: Fundamental and not so fundamental properties of spin echoes.Concepts Magn Reson 3: 125–143.
Hennig J (1988) Multi-echo imaging sequences with low refocusing flip-angles.J Magn Reson 78: 397–407.
Feinberg DA, Hale JD, Watts JC, Kaufman L, Mark A (1986) Halfing MR imaging time by conjugation: Demonstration at 3,5 kG.Radiology 161: 527.
Kaiser R, Bartholdi E, Ernst RR (1974) Diffusion and field-gradient effects in NMR Fourier spectroscopy.J Chem Phys 60: 2966–2979.
Hahn EL (1950) Spin echoes.Phys Rev 80: 580–594.
Woessner DE (1961) Effects of diffusion in nuclear magnetic resonance spin-echo experiments.J Chem Phys 34: 2057–2061.
Doddrell DM, Bulsing JM, Galloway GJ, Brooks WM, Field J, Irving MR, Baddeley H. Discrete isolation from gradient governed elimination of resonances. DIGGER, a new technique for in vivo volume selected NMR spectroscopy.
Morris GA, Freeman R (1978) Selective excitation in Fourier transform nuclear magnetic resonance.J Magn Reson 29:
Belliveau JW, Kennedy DN, McKinstry RC, Buchbinder BR, Weisskoff RM, Cohen MS, Vevea JM, Brady TJ, Rosen BR. Functional mapping of the human visual cortex by nuclear magnetic resonance.
LeRoux P, Pauly J, Macovski A (1991) Burst excitation pulses.Proc. Xth. Ann. Meeting SMRM p. 269.
Hennig J (1990) Generalized MR interography.Magn Reson Med 16: 390–402.
Zerhouni EA, Parish DM, Rogers WJ, Yang A, Shapiro EP (19) Human heart: tagging with MR imaging — a method for noninvasive assessment of myocardial motion.Radiology 169: 59–63.
Axel L, Dougherty L (1989) MR imaging of motion with spatial modulation of magnetization.Radiology 171: 841–845.
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