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Factors involved in the modulation of cell proliferation in vivo and in vitro: The role of fibroblast and epidermal growth factors in the proliferative response of mammalian cells

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  • Mechanisms of Cellular Control
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Summary

The control of proliferation of mesoderm-derived cells by EGF and FGF has been examined taking, as an example, the vascular endothelium. The mechanisms by which cell proliferation can be brought to a stop in vivo and in vitro have been reviewed.

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Authors and Affiliations

  1. Cancer Research Institute, University of California, 94143, San Francisco, California

    D. Gospodarowicz, G. Greenburg, H. Bialecki & B. R. Zetter

  2. Department of Medicine, University of California, 94143, San Francisco, California

    D. Gospodarowicz, G. Greenburg, H. Bialecki & B. R. Zetter

  3. School of Medicine, 94143, San Francisco, California

    D. Gospodarowicz, G. Greenburg, H. Bialecki & B. R. Zetter

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  1. D. Gospodarowicz
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This work was supported by Grants HL20-197 and HD 11082 from the National Institutes of Health, and VC-194 from the American Cancer Society. B. R. Zetter was supported by Fellowship 5-F32-CA05149-02 from the U.S. Public Health Service.

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Gospodarowicz, D., Greenburg, G., Bialecki, H. et al. Factors involved in the modulation of cell proliferation in vivo and in vitro: The role of fibroblast and epidermal growth factors in the proliferative response of mammalian cells. In Vitro 14, 85–118 (1978). https://doi.org/10.1007/BF02618177

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