Summary and Conclusions
After concluding this report of their comprehensive investigation, the authors made these further observations:
Villous patterns can be found in adenomas, villous adenomas, papillomas, papillary adenocarcinomas and many neoplasms of the colon and rectum.
Villous patterns were observed in 45 per cent of adenomas in their series, usually occurring in large tumors, in the older age group, and associated with greater frequency when there was cellular atypia.
Pedunculated forms may occur and, to make a diagnosis, microscopic as well as macroscopic criteria are essential.
In villous adenomas there is a high incidence of malignant transformation and frequently these lesions are associated with separate benign or malignant tumors of the colon and rectum.
In its pure form, villous papilloma is a tumor that is relatively rare and it behaves, essentially, like a villous adenoma.
A negative biopsy does not exclude the possibility that malignant change may exist in another portion of a villous adenoma.
Similar content being viewed by others
References
Castleman, B. and H. I. Krickstein: Do adenomatous polyps of the colon become malignant? New England J. Med.267: 469, 1962.
Enterline, H. T., G. W. Evans, R. Mercado-Lugo, L. Miller and W. T. Fitts, Jr.: Malignant potential of adenomas of colon and rectum. J.A.M.A.179: 110, 1962.
Mackie, J. A., Jr., L. D. Miller and W. T. Fitts, Jr.: Polyps and polypoid lesions of the large bowel: Surgical considerations. S. Clin. North America.42: 1451, 1962.
Morson, B. C.: Precancerous lesions of the colon and rectum. J.A.M.A.179: 316, 1962.
Spratt, J. S., Jr., L. V. Ackerman and C. A. Moyer: Relationship of polyps of the colon to colonic cancer. Ann. Surg.148: 682, 1958.
Sunderland, D. A. and G. E. Binkley: Papillary adenomas of large intestine. Cancer.1: 184, 1948.
Welch, J. S. and M. B. Dockerty: Villous carcinoma of the colon. Dis. Colon & Rectum.1: 251, 1958.
Wheat, M. W., Jr., and L. V. Ackerman: Villous adenomas of the large intestine. Ann. Surg.147: 476, 1958.
Author information
Authors and Affiliations
Additional information
Abridgment of original article read at the joint meeting of the American Proctologic Society and the Section of Proctology of the Royal Society of Medicine, Philadelphia, Pennsylvania, May 9 to 14, 1964.
About this article
Cite this article
Ferraro, L.R., Ross, S.T. Evaluation of villous patterns in tumors of the colon and rectum. Dis Colon Rectum 8, 144–148 (1965). https://doi.org/10.1007/BF02617080
Issue Date:
DOI: https://doi.org/10.1007/BF02617080