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The role of Ileal contents in the spontaneous regression of rectal adenomas

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Diseases of the Colon & Rectum

Summary and Conclusions

Spontaneous regression of adenomatous polyps of the rectum occurred in a patient with familial polyposis of the colon following ileoproctostomy alone, and with the defunctionalized unremoved portion of the colon remaining for a period of ten months.

On the basis of these observations it is suggested that the ileal fluid contains growth-inhibiting properties which may neutralize a growth-inducing stimulus believed to be present in the mucosa of the large bowel of patients with colonic polyposis.

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Author information

Authors and Affiliations

  1. the Department of Surgery, Western Reserve University and University Hospitals of, Cleveland, Ohio

    Jack W. Cole M.D., Anne McKalen B.S. & Jean Powell M.D.

Authors
  1. Jack W. Cole M.D.
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  2. Anne McKalen B.S.
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  3. Jean Powell M.D.
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Additional information

Read at the meeting of the American Proctologic Society, Pittsburgh, Pennsylvania, June 21 to 24, 1961.

This study was supported by the American Cancer Society Grant #T-169.

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Cole, J.W., McKalen, A. & Powell, J. The role of Ileal contents in the spontaneous regression of rectal adenomas. Dis Colon Rectum 4, 413–418 (1961). https://doi.org/10.1007/BF02616574

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  • DOI: https://doi.org/10.1007/BF02616574

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