Abstract
Objective:To determine the prevalence of acute cardiac ischemia in emergency department (ED) syncope patients without chest pain and to determine which of these patients are at high risk for acute cardiac ischemia.
Design:Data were collected prospectively during a study of ED triage of patients who had had possible acute cardiac ischemia. Supplemental retrospective review of records was performed to differentiate syncope from dizziness.
Setting:Six hospital EDs in New England (two primary teaching hospitals in urban locations, two medical-school-affiliated teaching hospitals, and two nonteaching hospitals in rural settings).
Patients:5,762 patients had presented to the ED with chief complaints consistent with acute cardiac ischemia, including chest pain, shortness of breath, dizziness, and syncope. The study sample consisted of 251 patients who had had syncope and no chest pain.
Results:The prevalence of acute cardiac ischemia among the syncope patients was 7% (18 of the 251 patients). Univariate analysis revealed the following to have significant association with acute cardiac ischemia: ischemic abnormalities on the electrocardiogram (ECG) obtained in the ED (p<0.001), arm or shoulder pain on presentation (p<0.05), rales (p<0.1), and prior history of exercise-induced angina (p<0.05) or myocardial infarction (p<0.1). All 18 patients with acute cardiac ischemia had ischemic abnormalities (pathologic Q waves, ST-segment elevation or depression, or T-wave abnormalities) on their presenting ECGs.
Conclusion:For syncope patients who have no chest pain or ischemic abnormality on the presenting ECG in the ED, acute ischemia appears to be unlikely. Admission to the cardiac care unit for these patients for possible myocardial ischemia is probably unnecessary. However, patients who have syncope and ischemic abnormalities on the ECG are at risk for acute cardiac ischemia, even in the absence of chest pain. Hospital admission to rule out myocardial infarction for these patients is prudent.
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Received from the Center for Cardiovascular Health Services Research, Divisions of Clinical Decision Making and General Medicine, Department of Medicine, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts.
Supported by the Agency for Health Care Policy and Research grants #RO1HS02068 and RO1HS05549. Dr. Georgeson was supported by grants from the National Library of Medicine (5 RO1 LM04493-05 and 5 T15 LM07044-06) and from the John A. Hartford Foundation (87269-3H), New York, NY.
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Georgeson, S., Linzer, M., Griffith, J.L. et al. Acute cardiac ischemia in patients with syncope. J Gen Intern Med 7, 379–386 (1992). https://doi.org/10.1007/BF02599151
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DOI: https://doi.org/10.1007/BF02599151