Summary
We believe this preoperative combined therapy is highly effective in treating squamous-cell carcinoma of the anal canal, and that a subsequent larger cooperative study with controls is indicated. This pilot study suggests that some individuals may be spared abdominoperineal resection when treated in the manner described.
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References
Newman HC, Quan SH: Multi-modality therapy for epidermoid carcinoma of the anus. Cancer 37:12, 1976
Nigro N, Vaitkevicius VK, Considine B Jr: Combined therapy for cancer of the anal canal: A preliminary report. Dis Colon Rectum 17:354, 1974
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Department of Oncology
Department of Surgery
Department of Radiotherapy
Supported in part by Clinical Cancer Research Center Grant CA-07177 from the National Cancer Institute, United States Public Health Service.
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Buroker, T.R., Nigro, N., Bradley, G. et al. Combined therapy for cancer of the anal canal: A follow-up report. Dis Colon Rectum 20, 677–678 (1977). https://doi.org/10.1007/BF02586688
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DOI: https://doi.org/10.1007/BF02586688