Skip to main content
SpringerLink
Log in

Quantification of cardiac function by conventional and cine magnetic resonance imaging

  • Published:
CardioVascular and Interventional Radiology Aims and scope Submit manuscript

Abstract

Magnetic resonance imaging (MRI) has been effective for depicting cardiac anatomy and is already established as a technique for the evaluation of some structural abnormalities of the heart and pericardium. With recent advances, MRI can now be used to quantitate cardiac function. Multiphasic ECG-gated spin-echo imaging has been used to quantitate right and left ventricular volumes and ejection fraction. left ventricular mass, and regional myocardial wall thickening. The new technique of cine MRI acquires frames during the cardiac cycle with a time resolution corresponding to 20 msec up to approximately 40 frames for an average cardiac cycle. This technique uses narrow flip angle (30°) and gradient refocused echoes. Cine MRI has been used to measure ventricular volumes and ejection fraction and regional myocardial wall thickening. It is also sensitive to the detection of valvular regurgitation and can provide quantitation of regurgitant volume. This article reviews the current status of MRI for quantitating cardiac function.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Worthington BS, Doyle M, Chapman B, Turner R, Ordidge RJ, Cawley M, Coxon, R, Glover P, Coupland RE, Morris GK, Mansfield P (1986) Real-time cardiac imaging of adults using variations of echo-planar imaging (abstract). Radiology 161 (P):338.

    Google Scholar 

  2. Crooks LE, Barker B, Chang H, Feinberg D, Hoenninger JC, Watts JC, Arakawa M, Kaufman L, Sheldon PE, Botvinick E, Higgins CB (1984) Magnetic resonance imaging strategies for heart studies. Radiology 153:459–465

    PubMed  CAS  Google Scholar 

  3. Byrd BF, Schiller NB, Botvinick EH, Higgins CB (1985) Normal cardiac dimensions by magnetic resonance imaging. Am J Cardiol 55:1440–1442

    Article  PubMed  Google Scholar 

  4. Kaul S, Wismer GL, Brady TJ, Johnston DL, Weyman AE, Okada RD, Dinsmore RE (1986) Measurement of normal left heart dimensions using optimally oriented MR images. Am J Roentgenol 146:75–79.

    CAS  Google Scholar 

  5. Stratemeier EJ, Thompson R, Brady TJ, Miller SW, Saini S., Wismer GL, Okada RD, Dinsmore RE (1986) Ejection fraction determination by MR imaging: Comparison with left ventricular angiography. Radiology 158:775–777

    PubMed  CAS  Google Scholar 

  6. Buckwalter KA, Aisen AM, Dilworth LR, Mancine GBJ, Buda AJ (1986) Gated cardiac MRI: Ejection fraction determination using the right anterior oblique view. Am J Roentgenol 147:33–37

    CAS  Google Scholar 

  7. Markiewicz W, Sechtem U, Kirby R, Derugin N, Caputo G, Higgins CB (1987) Measurement of ventricular volumes by MRI. J Am Col Cardiol 10:170–177.

    Article  CAS  Google Scholar 

  8. Rehr RB, Malloy, CR, Filipchuk NG, Peshock RM (1985) Left ventricular volumes measured by MR imaging, Radiology 156:717–719

    PubMed  CAS  Google Scholar 

  9. Underwood SR, Klipstein RH, Firmin DN, Fox KM, Poole-Wilson PA, Rees RSO, Longmore DB (1986) Magnetic resonance quantification of atrial shunting and valvular regurgitation (abstract). Magn Res Imaging 4:148

    Article  Google Scholar 

  10. Fisher M, von Schulthess GK, Higgins CB (1985) Multiphasic cardiac magnetic resonance imaging: Normal regional left ventricular wall thickening. Am J Roentgenol 145:27–30

    CAS  Google Scholar 

  11. Sechtem U, Sommerhoff BA, Markiewicz W, White RD, Cheitlin MD, Higgins CB (1987) Assessment of regional left ventricular wall thickening by magnetic resonance imaging: Evaluation in normal persons and patients with global and regional dysfunction. Am J Cardiol 59:145–151

    Article  PubMed  CAS  Google Scholar 

  12. Haase A, Matthaei D, Hänicke W, and Merboldt KD (1986) FLASH imaging. Rapid NMR imaging using low flip-angle pulses. J Magn Res 67:258–266.

    CAS  Google Scholar 

  13. van Dijk P, van der Meulen P, Pettigrew RI, Bluemm R, Dannels W, Doornbos J (1986) Dynamic studies of cardiac motion and flow with a fast multiphase MRI technique (abstract) J Am Coll Cardiol 7:197A

    Google Scholar 

  14. Schmalbrock P. Cornhill JF, Hunter WW, Stiving S (1986) Quantitative flow measurement using gradient recalled acquisition into the steady state (GRASS). Abstracts of the 5th Annual Meeting of the Society of Magnetic Resonance in Medicine (work in progress): 11–12.

  15. Sechtem U, Pflugfelder P, White RD, Cassidy MM, Cheitlin MD, Schiller NB, Higgins CB (1987) Quatification of regurgitant volumes in patients with mitral or aortic regurgitation by CINE MRI. Am J Cardiol (submitted for publication)

  16. Miyatake K, Okamoto M, Kinoshita N, Ohta M, Kozuka T, Sakakibara H, Nimura Y (1982) Evaluation of tricuspid regurgitation by pulsed Doppler and two-dimensional echocardiography Circulation 66:777–784

    PubMed  CAS  Google Scholar 

  17. Caputo GR (1986) Contour detection in high-speed cardiac MR images using a dynamic programming algorithm (abstract). Radiology 161 (P): 338

    Google Scholar 

  18. Sechtem U, Pflugfelder W, Would RG, Cassidy M, Higgins CB (1987) Measurement of right and left ventricular volumes in healthy individuals with cine MR imaging. Radiology 163:697–702

    PubMed  CAS  Google Scholar 

  19. Rackley CE (1976) Quantitative evaluation of left ventricular function by radiographic techniques. Circulation 54:862–879

    PubMed  CAS  Google Scholar 

  20. Gordon EP, Schnittger I, Fitzgerald PJ, Williams P, Popp RL (1983) Reproducibility of left ventricular volumes by two-dimensional echocardiography. J Am Coll Cardiol 2:506–513

    Article  PubMed  CAS  Google Scholar 

  21. Erbel R, Schweizer P, Henn G, Meyer J, Effert S (1982) Apikale zweidimensionale Echokardiographie. Normalwerte für die monoplane und biplane Bestimmung der Volumina und der Ejektionsfraktion des linken Ventrikels. Dtsch Med Wschr 107:1872–1877

    Article  PubMed  CAS  Google Scholar 

  22. Liebermann AN, Weiss JL, Judgutt BI, Becker LC, Bulkley BH, Garrison JG, Hutchins GM, Kallman CA, Weisfeldt ML (1981) Two dimensional echocardiography and infarct size: Relationship of regional wall motion and thickening to the extent of myocardial infarction in the dog. Circulation 63:739–746

    Google Scholar 

  23. Sechtem U, Pflugfelder PW, White RD, Gould RG, Holt W, Lipton MJ, Higgins CB (1987) CINE MRI: Potential for the evaluation of cardiovascular function. Am J Roentgenol 148:239–246

    CAS  Google Scholar 

  24. Didier D, Higgins CB (1986) Identification and localization of ventricular septal defect by gated magnetic resonance imaging. Am J Cardiol 57:1363–1368

    Article  PubMed  CAS  Google Scholar 

  25. Dinsmore RE, Wismer GL, Guyer D, Thompson R, Liu P, Stratemeier E, Miller S, Okada R, Brady T (1985) Magnetic resonance imaging of the interatrial septum and atrial septal defects Am J Roentgenol 145:697–703

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiology, University of California Medical School, C-309, San Francisco, CA, 94143, USA

    Udo Sechtem, Peter Pflugfelder & Charles B. Higgins

Authors
  1. Udo Sechtem
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Peter Pflugfelder
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Charles B. Higgins
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Research fellow in magnetic resonance imaging supported by grant SE 441-2 from Deutsche Forschungsgenmeinschaft, Bonn, West Germany.

Research fellow in magnetic resonance imaging supported by a grant from the Canadian Heart Foundation.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Sechtem, U., Pflugfelder, P. & Higgins, C.B. Quantification of cardiac function by conventional and cine magnetic resonance imaging. Cardiovasc Intervent Radiol 10, 365–373 (1987). https://doi.org/10.1007/BF02577347

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02577347

Key words

Search

Navigation