Abstract
Although many substances have been tested in the search for an ideal dural substitute, an entirely satisfactory material has still not been found. The authors report an experimental study involving the closure of dural defects in rabbits with biomaterials developed from pig peritoneum and pericardium. Macroscopic and histologic examination, performed over a period between 15 and 45 days after implantation showed slight or no adhesion between the graft material and the cortex. No infection, CSF leakage, fistula or toxicity was noticed. The results demonstrated that these biomaterials could be used as satisfactory dural substitutes.
Similar content being viewed by others
References
Abbott WM, Dupree EL (1970) The procurement, storage and transplantation of lyophilised human cadaver dura mater. Surg Gynecol Obstet 130:112–118
Adegbite AB, Paine KWE, Rozdilsky B (1983) The role of neomembranes in formation of hematoma around silastic dura substitute. J Neurosurg 58:295–297
Bang-Zong X, Hong-xue P, Ke-Ming L, Xi-Jin C, Ying-Dei T, Yong-Lin L, Jian L (1988) Study and clinical application of a porcine biomembrane for the repair of dural defects. J Neurosurg 69:707–711
Chao Yi-C, Humphreys S, Penfield W (1940) A new method of preventing adhesions. The use of amnioplastin after craniotomy. Br M J 30:517–519
Cohen AR, Aleksic S, Ransohoff J (1989) Inflammatory reaction to synthetic dural substitute. J Neurosurg 70:633–635
Delustro F, Dash J, Keefe J, Elingsworth L (1990) Immune response to allogenic and xenogenic implants of collagen and collagen derivatives. Clin Orthop 260:263–279
Huertas J (1955) The use of orlon for dural replacement. J Neurosurg 12:550–554
Kleine DG, Arbor A (1965) Dural replacement resorbable collagen. Arch Surg 91:924–929
Laquerriere A, Yun J, Tiollier J, Hemet J, Tadie M (1993) Experimental evaluation bilayered human collagen as a dural substitute. J Neurosurg 78:487–491
Laun A, Tonn C, Jerusalem C (1990) Comparative study of lyophized human dura mater and lyophilized bovine pericardium as dural substitutes in neurosurgery. Acta Neurochir 107:16–21
Lehman RAW, Hayes GJ, Martins AN (1967) The use of adhesive and lyophilized dura in the treatment of cerebrospinal rhinorhea. Technical note. J Neurosurg 26:92–95
Lee JF, Odom GL, Tindall GT (1967) Experimental evaluation of silicone-coated Dacron and collagen fabric-film laminate as dural substitutes. J Neurosurg 27:558–564
Macfarlane MR, Symon L (1979) Lyophilised dura mater: experimental implantation and extended clinical neurosurgical use. J Neurol Neurosurg Psychiatry 42:854–858
Maurer PK, McDonald JV (1985) Vicryl (Polyglactin 910) mesh as a dural substitute. J Neurosurg 63:448–452
Morgan A, Disant F, Truy E (1989) Experimental study of collagen as eardrum graft support in dogs. Acta Otolaryngol (Stockh) 107:450–455
Nussbaum CE, Maurer PK, McDonald JV (1989) Vicryl (Polyglactin 910) mesh as a dural substitute in the presence of pia arachnoid injury. J Neurosurg 71:124–127
O'Neill P, Booth A (1984) Use of porcine dermis as a dural substitute in 72 patients. J Neurosurg 61:351–354
Robertson RCL, Peacher WG (1945) The use of tantalium foil in the subdural space. J Neurosurg 2:281–284
Simpson D, Robson A (1984) Recurrent subaarchnoid bleeding in association with dural substitute. J Neurosurg 60:408–409
Thadani V, Penar PL, Partington J, Kalb R, Janssen R, Schonberger LB, Rabkin CS, Prichard JW (1988) Creutzfeldt-Jakob disease probably acquired from cadaveric dura mater graft. J Neurosurg 69:766–769
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Gök, A., Zorludemir, S., Polat, S. et al. Experimental evaluation of peritoneum and pericardium as dural substitutes. Res. Exp. Med. 195, 31–38 (1995). https://doi.org/10.1007/BF02576771
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02576771