Abstract
Two patients with polypoid bile duct tumors associated with familial adenomatosis coli are presented. A jaundiced man, aged 63, had polypoid masses identified as adenocarcinoma in the common and hepatic ducts. The other patient, a 38-year-old woman undergoing surgery for duodenal adenomas, had a solitary benign adenoma of the distal common duct in addition to duodenal adenocarcinoma. Only one earlier report of bile duct polyps could be found in association with familial adenomatosis. These cases support the view that familial gastrointestinal adenomatosis is a systemic disease which is not restricted to the colon and rectum.
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References
Lockhart-Mummery JP. Causation and treatment of multiple adenomatosis of the colon. Ann Surg 1934;99:178–84.
Gardner EJ, Richards RC. Multiple cutaneous and subcutaneous lesions occurring simultaneously with hereditary polyposis and osteomatosis. Am J Hum Genet 1953;5:139–47.
Gardner EJ. Follow-up study of a family group exhibiting dominant inheritance for a syndrome including intestinal polyps, osteomas, fibromas, and epidermal cysts. Am J Hum Genet 1962;14:376–90.
Watanabe H, Enjoji M, Yao T, Ohsato K. Gastric lesions in familial adenomatosis coli. Hum Pathol 1978;9:269–83.
Yao T, Iida M, Ohsato K, Watanabe H, Omae T. Duodenal lesions in familial polyposis of the colon. Gastroenterology 1977; 73:1086–92.
Hamilton SR, Bussey HJR, Mendelsohn G, et al. Ileal adenomas after colectomy in nine patients with adenomatous polyposis coli/Gardner's syndrome. Gastroenterology 1979;77:1252–7.
Järvinen H, Nyberg M, Peltokallio P. Upper gastrointestinal tract polyps in familial adenomatosis coli. Gut (In press).
Schuchardt WA, Ponsky JL. Familial polyposis and Gardner's syndrome. Surg Gynecol Obstet 1979;148:97–103.
Jones TR, Nance FC. Periampullary malignancy in Gardner's syndrome. Ann Surg 1977;185:565–71.
Weinberger JM, Cohen Z, Berk T. Polyposis coli preceded by hepatocellular carcinoma: report of a case. Dis Colon Rectum 1981;24:296–300.
Börner B. Eine Papillomatose der intra-und extrahepatischen Gallenwege. Z Krebsforsch 1960;63:474–80.
Burney B, Assor D. Polyposis coli with adenocarcinoma associated with carcinoma in situ of the gallbladder. Am J Surg 1976;132: 100–2.
Lees CD, Hermann RE. Familial polyposis coli associated with bile duct cancer. Am J Surg 1981;141:378–80.
Burhans R, Myers RT. Benign neoplasms of the extrahepatic biliary ducts. Am Surg 1971;37:161–6.
Neumann RD, LiVolsi VA, Rosenthal NS, Burrell M, Ball TJ. Adenocarcinoma in biliary papillomatosis. Gastroenterology 1976;70:779–82.
Schoenfield LJ. Diseases of the gallbladder and biliary system. New York: John Wiley & Sons, 1977:293–9.
Sachatello CR. Familial polyposis of the colon: a four decade follow-up. Cancer 1971;28:581–7.
Turunen MJ, Kivilaakso EO. Increased risk of colorectal cancer after cholecystectomy. Ann Surg 1981;194:639–41.
Reddy BS, Mastromarino A, Gustafson C, Lipkin M, Wynder EL. Fecal bile acids and neutral sterols in patients with familial polyposis. Cancer 1976;38:1694–8.
Watne AL, Lai H-Y, Mance T, Core S. Fecal steroids and bacterial flora in patients with polyposis coli. Am J Surg 1976;131:42–6.
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Järvinen, H.J., Nyberg, M. & Peltokallio, P. Biliary involvement in familial adenomatosis coli. Dis Colon Rectum 26, 525–528 (1983). https://doi.org/10.1007/BF02563746
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DOI: https://doi.org/10.1007/BF02563746