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Factors affecting recurrence following resection for Crohn's disease

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Diseases of the Colon & Rectum

Abstract

The records of 187 patients with Crohn's disease who underwent resectional surgery were analyzed to evaluate the effect of several clinical and histologic features on the recurrence rate. Recurrence was defined as the need for re-resection. The data were analyzed by the life-table method. Age, sex, age at onset of disease and at time of resection, family history, presence of granuloma, and microscopic involvement at the line of resection did not affect the recurrence rate. The distribution of the disease and duration of symptoms before primary resection did influence the rate of re-resection. Patients with predominantly large bowel disease (N=56) were found to have a higher rate of re-resection (45 percent) when compared with 32 percent in patients with small bowel involvement (N=94) and with 35 percent in patients with both small and large bowel involvement (N=37) (P=0.04). a detailed review, an analysis of the literature, and a comparison with our results are made.

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Authors and Affiliations

  1. the State University of New York at Stony Brook, Stony Brook, New York

    Chashmae Chardavoyne M.D., George W. Flint M.D., Simcha Pollack Ph.D. & Leslie Wise M.D.

  2. Department of Surgery, Long Island Jewish Medical Center, 11042, New Hyde Park, New York

    Chashmae Chardavoyne M.D., George W. Flint M.D., Simcha Pollack Ph.D. & Leslie Wise M.D.

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  1. Chashmae Chardavoyne M.D.
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  2. George W. Flint M.D.
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  3. Simcha Pollack Ph.D.
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  4. Leslie Wise M.D.
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Chardavoyne, C., Flint, G.W., Pollack, S. et al. Factors affecting recurrence following resection for Crohn's disease. Dis Colon Rectum 29, 495–502 (1986). https://doi.org/10.1007/BF02562601

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  • DOI: https://doi.org/10.1007/BF02562601

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