Abstract
The non-linear differential eguation
is studied. It is the main aim of this paper to show the existence of bifurcation of saddle connection type; and to show the creation of limit cycles under certain conditions of the parameters, together with their biological significance.
Similar content being viewed by others
References
Lauffenburger, D.A. Kennedy, C.R., Analysis of a lumped model for tissue inflammation dynamics,Math. Bios.,53,(1981), 189–222.
Andronov, A.A., et al, Theore of bifurctions of dynamic system on a plane, New York, 1973.
Bautin, N., Methods and principle of qualitative investigation of dynamic systems on a plane, Moscow, 1976.
Andronov, A.A., et al, Theory of oscillations Moscow, 1959.
Metchnikoff, E., Lectures on the comparative pathology of inflammation, Dover, 1968.
Hersh, E.M., Budey, G., Leukocyte mechanisms in inflammation,Ann. Rev. Med.,21(1970), 105–132.
Lauffenbuger, D.A., Effects of motility and chemotaxis in cell population dynamical system, Ph.D. Thesis, Univ. of Minnesota, 1979.
Lauffenburger, D.A., Mathematical model for tissue inflammation: Effects of spatial distribution, cell motility, and chemotaxis,Lecture Notes in Biomathematics,38(1980) 397–407.
Lauffenburger, D.A. Leller, K.H., Effects of leukocyte reandom motility and chemotoxis in tussue, inflammatoryy response,J. Theoret. Biol.,81(1979), 475–503.
Ye Yanqian, Theory of limit cycle, Shanghai, China, 1959.
Qin Yuanxun, Integral curves of ordinary differential equations, Beijing, China, 1959.
Ding Tongren, Fundamental theory of ordinary differential equations, Shanghai, China, 1981.
Zhang Zhifen, et al., Qualitative theory of ordinary differential equations, Beijing, China, 1985.
Zhang Jinyan, Geometric theory and bifurcation theory of ordinary differential equations, Beijing University press, 1981.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Zhujun, J. Qualitative analysis of a mathematical model for tissue inflammation dynamics. Acta Mathematica Sinica 3, 327–339 (1987). https://doi.org/10.1007/BF02559913
Received:
Revised:
Issue Date:
DOI: https://doi.org/10.1007/BF02559913