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Cathartic colon

Reversibility of roentgen changes

  • Published:
Diseases of the Colon & Rectum

Abstract

Cathartic colon is an infrequent and severe manifestation of chronic irritant laxative abuse. Little is known of its natural history after cathartics are stopped. Previous reported cases have shown residual roentgen abnormalities on follow-up examinations. A case is presented of cathartic colon caused by more than 70 years of laxative abuse that demonstrated complete reversal of the roentgen changes four months after stopping the medication. Some pathophysiologic correlates of this dramatic reversibility are discussed.

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References

  1. Heilbrun N. Roentgen evidence suggesting enterocolitis associated with prolonged cathartic abuse. Radiology 1943;41:486–91.

    Google Scholar 

  2. Jewell FC, Kline JR. The purged colon. Radiology 1954;62:368–71.

    PubMed  CAS  Google Scholar 

  3. Heilbrun N, Bernstein C. Roentgen abnormalities of the large and small intestine associated with prolonged cathartic ingestion. Radiology 1955;65:549–56.

    PubMed  CAS  Google Scholar 

  4. Plum GE, Weber HM, Sauer WG. Prolonged cathartic abuse resulting in roentgen evidence suggestive of entercolitis. AJR 1960;83:919–25.

    CAS  Google Scholar 

  5. Ziter FM Jr. Cathartic colon. NY State J Med 1967;67:546–9.

    Google Scholar 

  6. Oster JR, Materson BJ, Rogers AI. Laxative abuse syndrome. Am J Gastroenterol 1980;74:451–8.

    PubMed  CAS  Google Scholar 

  7. Smith B. Pathologic changes in the colon produced by anthraquinone purgatives. Dis Colon Rectum 1973;16:455–8.

    PubMed  CAS  Google Scholar 

  8. Plumley PF. Radical surgery in the treatment of cathartic colon. Proc R Soc Med 1973;66:243–4.

    PubMed  CAS  Google Scholar 

  9. Todd IP. Cathartic colon: surgical aspects. Proc R Soc Med 1973;66:244–5.

    PubMed  CAS  Google Scholar 

  10. Earnest DL. Other diseases of the colon and rectum. In: Sleisenger MH, Fordtran JS, eds. Gastrointestinal disease: pathophysiology, diagnosis, management. 2nd ed. Philadelphia: WB Saunders, 1978:1863.

    Google Scholar 

  11. Heizer WD, Warshaw AL, Waldmann TA, Laster L. Protein-losing gastroenteropathy and malabsorption associated with factitious diarrhea. Ann Intern Med 1968;68:839–52.

    PubMed  CAS  Google Scholar 

  12. Lemaitre G, L'Herminé C, Decoulx M, Houcke M, Linquette M. Aspect radiologique des colites chroniques par abus de laxatifs. A propos de quatre observations. J Belge Radiol 1970;53:339–45.

    PubMed  CAS  Google Scholar 

  13. Hardcastle JD, Wilkins JL. The action of sennosides and related compounds on human colon and rectum. Gut 1970;11:1038–42.

    PubMed  CAS  Google Scholar 

  14. Riemann JF, Zimmermann W. Ultrastructural studies of colonic nerve plexuses in chronic laxative abuse (abstract). Gastroenterology 1978;74:1085.

    Google Scholar 

  15. Riemann JF, Schenk J, Ehler R, Schmidt H, Koch H. Ultrastructural changes of colonic mucosa in patients with chronic laxative misuse. Acta Hepato-Gastroenterol 1978;25:213–8.

    CAS  Google Scholar 

  16. Urso FP, Urso MJ, Lee CH. The cathartic colon: pathological findings and radiological/pathological correlation. Radiology 1975;116:557–9.

    PubMed  CAS  Google Scholar 

  17. Kim SK, Gerle RD, Rozanski R. Cathartic colitis. AJR 1978;131:1079–81.

    PubMed  CAS  Google Scholar 

  18. Wittoesch JH, Jackman RJ, McDonald JR. Melanosis coli: general review and a study of 887 cases. Dis Colon Rectum 1958;1:172–80.

    PubMed  CAS  Google Scholar 

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Campbell, W.L. Cathartic colon. Dis Colon Rectum 26, 445–448 (1983). https://doi.org/10.1007/BF02556523

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  • DOI: https://doi.org/10.1007/BF02556523

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