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Effects of ovariectomy on iliac trabecular bone in baboons (Papio anubis)

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Summary

Biopsies were collected from the left iliac crest of six adult female baboons, after which three of the animals were ovariectomized. Biopsies were collected from the right iliac crest six months later. Histomorphometric evaluation of the biopsies revealed consistent increases in fractional forming surface, appositional rate, and volume-based bone formation rate after ovariectomy. The data indicate that bone turnover is increased following ovariectomy in the baboon.

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Authors and Affiliations

  1. Department of Comparative Medicine, Bowman Gray School of Medicine, 27103, Winston-Salem, North Carolina, USA

    C. P. Jerome & D. S. Weaver

  2. Department of Anthropology, Wake Forest University, 27103, Winston-Salem, North Carolina, USA

    D. S. Weaver

  3. The Bone Metabolic Laboratory, The Orthopaedic Hospital, 28207, Charlotte, North Carolina, USA

    D. B. Kimmel & J. A. McAlister

Authors
  1. C. P. Jerome
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  2. D. B. Kimmel
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  3. J. A. McAlister
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  4. D. S. Weaver
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Jerome, C.P., Kimmel, D.B., McAlister, J.A. et al. Effects of ovariectomy on iliac trabecular bone in baboons (Papio anubis). Calcif Tissue Int 39, 206–208 (1986). https://doi.org/10.1007/BF02555119

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  • DOI: https://doi.org/10.1007/BF02555119

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