Abstract
The effect of an intraluminal tube on the healing of an inadequately constructed colonic anastomosis was evaluated. An anastomosis using a single suture was constructed in 78 rats divided into four experimental groups. In one, a latex tube was sited intraluminally at the level of the anastomosis and removed transanally after, six days. In the second, a soft tube consisting of rat duodenum preserved in 5 percent formalin was similarly sited and allowed to pass spontaneously. In the third group, the formalin tube was placed outside the colon surrounding the anastomosis. The fourth group was a control. The mortality, of the latex intraluminal tube group was 48 percent, the intraluminal duodenum in formalin group 29 percent (significantly less than the control group,P<.02), the extraluminal tube around the anastomosis group 100 percent, and the control group 75 percent (P<.02). There was no significant difference among the experimental groups in the mean breaking strength of the colonic anastomosis in the 28-day survivors.
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This study was supported by the Leslie Broons Trust.
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Ross, H. The effect of an intralminal tube used as an internal drain on the healing of the rat colon. Dis Colon Rectum 30, 591–594 (1987). https://doi.org/10.1007/BF02554804
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DOI: https://doi.org/10.1007/BF02554804