Abstract
In a review of 1037 patients with colorectal cancers, there were 32 patients below the age of 40 years (3 percent). Rectal bleeding and abdominal pain were the most common presenting symptoms. The average delay between the onset of symptoms and treatment was 6.5 months. An analysis of tumors according to Dukes' staging revealed no significant difference between young and elderly patients. The younger patients had a greater frequency of mucinous and poorly differentiated carcinoma. When compared by clinical staging, however, the young patient did as well or better than his older counterpart. Clinical staging was the most important prognostic factor, irrespective of age. No inherent difference was found in the virulence of the cancer in the young, and five-year survival rates were not significantly different in young and old patients (59 percent vs. 49 percent).
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Falterman KW, Hill CB, Markey JC, Fox JW, Cohn I Jr. Cancer of the colon, rectum, and anus: a review of 2313 cases. Cancer 1974;34:951–9.
Kern WH, White WC. Adenocarcinoma of the colon in a 9-month-old infant: report of a case. Cancer 1958;11:855–7.
Chabalko JJ, Fraumeni JF Jr. Colorectal cancer in children: epidemiologic aspects. Dis Colon Rectum 1975;18:1–3.
Ezzo JA, Sullivan JF, Mack RE. Carcinoma of the colon under the age of 40. Ann Intern Med 1958;49:321–5.
Hall A, Coffey RJ. Cancer of the large bowel in the young adult. Am J Surg 1961;102:66–72.
Lundy J, Welch JP, Berman M. Colorectal cancer in patients under 40 years of age. J Surg Oncol 1983;24:11–4.
Moore PA, Dilawari RA, Fidler WJ. Adenocarcinoma of the colon and rectum in patients less than 40 years of age. Am Surg 1984; 50:10–4.
Pitluk H, Poticha SM. Carcinoma of the colon and rectum in patients less than 40 years of age. Surg Gynecol Obstet 1983; 57:335–7.
Coffey RJ, Cardenas F. Cancer of the bowel in the young adult. Dis Colon Rectum 1964;7:491–2.
Gallagher EG, Zeigler MG. Rectal carcinoma in patients in the second and third decades of life. Am J Surg 1972;124:655–9.
Johnson JW, Judd ES, Dahlin DC. Malignant neoplasms of the colon and rectum in young persons. Arch Surg 1959;79:365–72.
Mayo CW, Pagtalunan RJ. Malignancy of colon and rectum in patients under 30 years of age. Surgery 1963;53:711–8.
Rosato FE, Frazier TG, Copeland EM, Miller LD. Carcinoma of the colon in young people. Surg Gynecol Obstet 1969;129:29–32.
Howard EW, Cavallo C, Hovey LM, Nelson TG. Colon and rectal cancer in the young adult. Am Surg 1975;41:260–5.
Rigby CS, Subramony C, Kukora JS. Carcinoma of the colon and rectum in adolescents and young adults. Surg Gastroenterol 1983; 2:283–8.
Sanfelippo PM, Beahrs OH. Carcinoma of the colon in patients under forty years of age. Surg Gynecol Obstet 1974;138:169–70.
Scarpa FJ, Hartmann WH, Sawyers JL. Adenocarcinoma of the colon and rectum in young adults. South Med J 1976;69:24–7.
van Langenberg A, Ong GB. Carcinoma of large bowel in the young. Br Med J 1972;3:374–6.
Recio P, Bussey HJ. The pathology and prognosis of carcinoma of the rectum in the young. Proc R Soc Med 1965;58:789–90.
Simstein NL, Kovalcik PJ, Cross GH. Colorectal carcinoma in patients less than 40 years of age. Dis Colon Rectum 1978; 21:169–71.
Qualheim RE, Gall EA. Is histologic grading of colon carcinoma a valid procedure? Arch Pathol 1953;56:466–72.
Anderson WA. Pathology, 5th ed. St. Louis: CV Mosby, 1966:874.
Buchman JA, Calhoum JD. Colloid carcinoma of the colon in children. Am Surg 1958;24:280–6.
Walton WW Jr, Hagihara PF, Griffen WO Jr. Colorectal adenocarcinoma in patients less than 40 years old. Dis Colon Rectum 1976;19:529–34.
Ohman U. Colorectal carcinoma in patients less than 40 years of age. Dis Colon Rectum 1982;25:209–14.
Roth-Moyo LA, Devitt JE, Brown FN. The effect of age on the behavior of carcinoma of the colon and rectum. Dis Colon Rectum 1968;11:420–2.
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Adloff, M., Arnaud, JP., Schloegel, M. et al. Colorectal cancer in patients under 40 years of age. Dis Colon Rectum 29, 322–325 (1986). https://doi.org/10.1007/BF02554121
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DOI: https://doi.org/10.1007/BF02554121