Skip to main content
Log in

Clinical and operative experience with non-caucasian patients with Crohn's disease

  • Published:
Diseases of the Colon & Rectum

Abstract

Fifteen black patients with Crohn's disease were seen during a ten-year period (1975–1985). They represented 11 percent of our experience with Crohn's disease during that time. These patients had an earlier age of onset of Crohn's symptoms than our white patients, and correct diagnosis was delayed for an average of four years. All 15 patients required abdominal surgery, and seven (47 percent) suffered recurrences necessitating additional abdominal operations. The five-year actuarial estimate of probability of reoperation was 77 percent. Extraintestinal manifestations were present in all patients, and six (40 percent) had multiple manifestations. These disease manifestations are more severe than those noted in series that studied predominantly caucasian Crohn's populations, and suggest that Crohn's disease in the black patient is a distinctly aggressive form.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Mekhjian HS, Switz DM, Melnyk CS, Rankin GB, Brooks RK. Clinical features and natural history of Crohn's disease. Gastroenterology 1979;77:898–906.

    PubMed  CAS  Google Scholar 

  2. Rogers BH, Clark LM, Kirsner JB. The epidemiologic and demographic characteristics of inflammatory bowel disease: an analysis of a computerized file of 1400 patients. J Chronic Dis 1971;24:743–73.

    Article  PubMed  CAS  Google Scholar 

  3. Mendeloff AI, Monk M, Siegel CI, Lilienfeld A. Some epidemiological features of ulcerative colitis and regional enteritis. Gastroenterology 1966;51:748–56.

    PubMed  CAS  Google Scholar 

  4. Wright JP, Marks IN, Jameson C, Garisch JA, Burns DG, Kottler RE. Inflammatory bowel disease in Cape Town, 1975–1980. South Afr Med J 1983;63:226–9.

    CAS  Google Scholar 

  5. Bremner CG, Ackerman LV. Polyps and carcinoma of the large bowel in the South African Bantu. Cancer 1970;26:991–9.

    Article  PubMed  CAS  Google Scholar 

  6. Davis R, Schmaman A, Cosman B. Crohn's disease in Transvaal blacks. South Afr Med J 1974;48:580–6.

    CAS  Google Scholar 

  7. Pillay SP, Moshal MG, Spitaels JM, et al. Etiology of colonic strictures in South African black and Indian patients. Dis Colon Rectum 1981;24:107–13.

    PubMed  CAS  Google Scholar 

  8. Farmer RC. Medical management and indications for surgery in Crohn's disease. In: Kodner I, Fry R, Roe J, eds. Controversial topics in colon and rectal surgery. St. Louis: CV Mosby, 1985;233–42.

    Google Scholar 

  9. Best WR, Becktel JM, Singleton JW. Rederived values of the eight coefficients of the Crohn's Disease Activity Index (CDAI). Gastroenterology 1979;77:843–6.

    PubMed  CAS  Google Scholar 

  10. Lennard-Jones JE, Stalder GA. Prognosis after resection of chronic regional ileitis. Gut 1967;8:332–6.

    PubMed  CAS  Google Scholar 

  11. Acheson ED. The distribution of ulcerative colitis and regional enteritis in United States veterans, with particular reference to the Jewish religion. Gut 1960;1:291–3.

    PubMed  CAS  Google Scholar 

  12. Giraud RM, Luke I, Schmaman A. Crohn's disease in the Transvaal Bantu: a report of 5 cases. South Afr Med J 1969;43:610–3.

    CAS  Google Scholar 

  13. Bartholomew C, Butler A. Inflammatory bowel disease in the West Indies. Br Med J 1979;2:824–5.

    Article  PubMed  CAS  Google Scholar 

  14. Walker AR, Segal I. Epidemiology of noninfective intestinal diseases in various ethnic groups in South Africa. Isr J Med Sci 1979;15:309–13.

    PubMed  CAS  Google Scholar 

  15. Samuels A, Weese J, Berman P, Kirsner J. An epidemiologic and demographic study of inflammatory bowel disease in black patients. Dig Dis Sci 1974;19:156–60.

    Article  CAS  Google Scholar 

  16. Mosley E Jr, Rogers N, Scott V, Chung EB, Press HC Jr, Leffall LD Jr. Crohn's disease in black patients. J Natl Med Assoc 1977; 69:219–22.

    PubMed  Google Scholar 

  17. Farmer RG, Hawk WA, Turnbull RB Jr. Clinical patterns in Crohn's disease: a statistical study of 615 cases. Gastroenterology 1975;68:627–35.

    PubMed  CAS  Google Scholar 

  18. Agrez MV, Valente RM, Pierce W, Melton LJ III, Van Heerden JA, Beart RW Jr. Surgical history of Crohn's disease in a well-defined population. Mayo Clin Proc 1982;57:747–52.

    PubMed  CAS  Google Scholar 

  19. Mekhjian HS, Switz DM, Watts HD, Deren JJ, Katon RM, Beman FM. National Cooperative Crohn's Disease Study: factors determining recurrence of Crohn's disease after surgery. Gastroenterology 1979;77:907–13.

    PubMed  CAS  Google Scholar 

  20. Homan WP, Dineen P. Comparison of the results of resection, bypass, and bypass with exclusion for ileocecal Crohn's disease. Ann Surg 1978;187:530–5.

    Article  PubMed  CAS  Google Scholar 

  21. Rankin GB, Watts HD, Melnyk CS, Kelley ML Jr. National Cooperative Crohn's Disease Study: extraintestinal manifestations and perianal complications. Gastroenterology 1979;77:914–20.

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Read at the meeting of the American Society of Colon and Rectal Surgeons, San Diego, California, May 5 to 10, 1985.

About this article

Cite this article

Goldman, C.D., Kodner, I.J., Fry, R.D. et al. Clinical and operative experience with non-caucasian patients with Crohn's disease. Dis Colon Rectum 29, 317–321 (1986). https://doi.org/10.1007/BF02554120

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02554120

Key words

Navigation