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Sertraline in the treatment of premature ejaculation: A double-blind placebo controlled study

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Abstract

This study investigated the efficacy and the adverse effects of sertraline in the treatment of premature ejaculation (PE). Thirty-seven patients with PE were randomly assigned to receive either sertraline or a placebo. Of them 22 were given 50 mg of sertraline per day and the other 15 patients were given an identical placebo one per day. After 4 weeks, the latency to ejaculation in the sertraline group was found to be significantly longer than that of the placebo group (p<0.01). None of the patients discontinued therapy due to adverse effects. These results indicate that sertraline is an effective therapy for PE.

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Authors and Affiliations

  1. Department of Urology, Medical School of Gazi University, Ankara, Turkey

    H. Biri, K. Isen, Z. Sinik, M. Onaran, B. Küpeli & I. Bozkirli

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  1. H. Biri
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  2. K. Isen
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  3. Z. Sinik
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  4. M. Onaran
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  5. B. Küpeli
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  6. I. Bozkirli
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Biri, H., Isen, K., Sinik, Z. et al. Sertraline in the treatment of premature ejaculation: A double-blind placebo controlled study. International Urology and Nephrology 30, 611–615 (1998). https://doi.org/10.1007/BF02550555

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  • DOI: https://doi.org/10.1007/BF02550555

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