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Metastasis to the penis case reports and review of the literature

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Abstract

Metastasis to the penis is rare, despite rich vascularization and complex circulation. Less than 200 cases have been reported. Three new cases of penis metastasis from primary tumours in the bladder and prostate, respectively, are described.

The most common symptoms are penile induration and swelling.

Treatments, all of which must be considered merely palliative, consist of local tumour excision, radiation therapy, cytostatic and hormone therapy, possibly with partial or total penis amputation.

The prognosis is poor, irrespective of the therapy and site of the primary tumour. More than 80% of the patients die within six months after the occurrence of penis metastasis, as a result of disseminated cancer disease.

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References

  1. Abeshouse, B. S., Abeshouse, G. A.: Metastatic tumors of the penis: a review of the literature and a report of two cases.J. Urol., 86, 99 (1961).

    PubMed  CAS  Google Scholar 

  2. Anderson, W. A. D., Scotti, T. M.: Synopsis of Pathology. 10th edition. C. V. Mosby, St. Louis 1980, pp. 247–250.

    Google Scholar 

  3. Bosch, P. C., Forbes, K. A., Kollin, J., Golji, H., Miller, J. B.: Secondary carcinoma of the penis.J. Urol., 132, 990 (1984).

    PubMed  CAS  Google Scholar 

  4. Callen, J. P., Gruber, G. G., Giannini, J. M.: Metastatic colonic adenocarcinoma to the glans penis.Int. J. Dermatol., 9, 540 (1982).

    Google Scholar 

  5. Currie, G., Cancer and the Immune Response. 2nd edition. Edward Arnold, London 1980.

    Google Scholar 

  6. Garnick, M. B., Skarin, A. T., Steele, G. D.: Metastatic carcinoma of the penis: Complete remission after high dose methotrexate chemotherapy.J. Urol., 122, 265 (1979).

    PubMed  CAS  Google Scholar 

  7. Jensen, M. S.: Cancer penis. Copenhagen, F. A. D. L. 1976 (Thesis).

  8. Jepsen, J. M., Pedersen, J. K., Andersen, J.: Cancer of the prostate with metastasis to the penis.Ugeskr. Laeger., 143, 2236 (1981).

    PubMed  CAS  Google Scholar 

  9. Kumar, P. P., Newland, J. R.: Metastatic carcinoma of the penis.J. Nat. Med. Assoc., 1, 55 (1980).

    Google Scholar 

  10. Kyriakidis, A., Papacharalambous, G., Economacos, G.: Metastatic carcinoma of the penis: case report.Acta Urol. Belg., 4, 702 (1979).

    Google Scholar 

  11. Lund, F.: Priapism caused by metastasis to the penis.Ugeskr. Laeger., 123, 346 (1961).

    PubMed  CAS  Google Scholar 

  12. May, F., Hirtl, H.: Das Cavernosogramm.Urol. Int., 2, 120 (1955).

    Google Scholar 

  13. McCrea, L. E., Karafin, L.: Carcinoma of the prostate with metastasis to the prepuce.J. Urol., 106, 588 (1971).

    Google Scholar 

  14. Narayana, A. S., Loening, S. A., Olney, L., Howard, D., Culp, D. A.: Metastatic tumors of the penis.Eur. Urol., 5, 262 (1979).

    PubMed  CAS  Google Scholar 

  15. Ney, C., Miller, H. L., Friedenberg, R. M.: Various applications of corpus cavernosography.Radiology, 119, 69 (1976).

    PubMed  CAS  Google Scholar 

  16. Oka, M., Nakashima, K.: Carcinoma of the prostate with metastasis to the skin and glans penis.Br. J. Urol., 54, 61 (1982).

    Article  PubMed  CAS  Google Scholar 

  17. Ordonez, N. G., Ayala, A. G., Bracken, R. B.: Renal cell carcinoma metastatic to penis.Urology, 4, 417 (1982).

    Article  Google Scholar 

  18. Paquin, A. J., Roland, S. I.: Secondary carcinoma of the penis.Cancer, 9, 626 (1956).

    Article  PubMed  Google Scholar 

  19. Patel, N. B., Ward, J. N.: Carcinoma of prostate metastatic to prepuce and glans penis.Urology, 3, 269 (1978).

    Article  Google Scholar 

  20. Robey, E. L., Schellhammer, P. F.: Four cases of metastasis to the penis and a review of the litarature.J. Urol., 132, 992 (1984).

    PubMed  CAS  Google Scholar 

  21. Smehaug, J.: Metastases to the penis from carcinoma of the prostate.Scand. J. Urol. Nephrol., 13, 205 (1979).

    Article  PubMed  CAS  Google Scholar 

  22. Spreen, S. A., Keys, R. H., Evans, A. I.: Acute urinary retention secondary to metastatic prostatic carcinoma to the penis: a case report.J. Urol., 113, 59 (1975).

    PubMed  CAS  Google Scholar 

  23. Tan, H. T., Vishniavski, S.: Carcinoma of the prostate with metastasis to the prepuce.J. Urol., 106, 588 (1971).

    PubMed  CAS  Google Scholar 

  24. Trulock, T. S., Wheatley, J. K., Walton, K. N.: Secondary tumors of the penis.Urology, 6, 563 (1981).

    Article  Google Scholar 

  25. Wolf, H., Madsen, P. O.: Metastases to the external genitalia from carcinoma of the prostate: a report of two cases.J. Urol., 99, 198 (1968).

    PubMed  CAS  Google Scholar 

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Osther, P.J., Lóntoft, E. Metastasis to the penis case reports and review of the literature. International Urology and Nephrology 23, 161–167 (1991). https://doi.org/10.1007/BF02549714

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