Skip to main content

Advertisement

SpringerLink
Log in

A television scanning system for the measurement of the spatial variation of micro-density in bone sections

  • Original Papers
  • Published:
Calcified Tissue Research Aims and scope Submit manuscript

Abstract

The problems encountered in the determination of the spatial distribution of bone density on a microscopic scale are discussed. A critical appraisal is presented of the practical problems encountered when specimen plane, or source plane, scanning microdensitometers are used to assess bone mineral density distributions as represented by microradiographs of thin bone sections. An image plane television scanning system is presented as the best solution with results to support its selection.

Résumé

Les problèmes de l'analyse de la distribution spatiale de la densité osseuse sont envisagés à l'échelle microscopique. Une étude critique est réalisée lorsqu'on utilise un plan d'échantillon, un plan de source et des microdensitomètres à balayage pour déterminer la densité minérale osseuse à partir de microradiographies de fines coupes osseuses. Un système de télévision à balayage avec plan d'image semble être la meilleure solution.

Zusammenfassung

Die Probleme werden diskutiert, welche sich bei der Bestimmung der räumlichen Verteilung der Knochendichte auf einer mikroskopischen Skala ergeben. Es erfolgt eine kritische Beurteilung der praktischen Probleme beim Gebrauch von Scanning-Mikrodensitometern für planparallele Objekte oder homogene Lichtquellen, um damit die Verteilung der Knochenmineraldichte zu erfassen, wie sie in Mikroradiographien von dünnen Knochenschnitten dargestellt ist. Ein TV-Scanning-System wird als die beste Lösung vorgeschlagen, und es werden Resultate beigefügt, die für diese Wahl sprechen.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Atkinson, P. J., Weatherell, J. A.: Variation in the density of the femoral diaphysis with age. J. Bone Jt Surg. B49, 781–788 (1967).

    CAS  Google Scholar 

  • Davis, M. E., Strandjord, N. M., Lanzl, L. H.: Estrogens and the ageing process. J. Amer. med. Ass.196, 219–224 (1966).

    Article  CAS  Google Scholar 

  • Engfeldt, B., Engstrom, A., Zetterstrom, R.: Renewal of phosphate in bone minerals. II. Radioautographic studies of the renewal of phosphate in different structures of bone. Biochim. biophys. Acta (Amst.)8, 375–380 (1952).

    Article  CAS  Google Scholar 

  • Fisher, C. F.: An image analysing computer. Bio-Med. Engl.2, 351–357 (1967).

    Google Scholar 

  • Fisher, C. F.: The new Quantimet 720. Microscope19, 1–20 (1971).

    Google Scholar 

  • Fraser, S. A., Smith, D. A., Anderson, J. B., Wilson, G. M.: Osteoporosis in fractures following thyrotoxicosis. Lancet1971 I, 981–983.

  • McQueen, C. M., Monk, I. B., Horton, P. W., Smith, D. A.: Preparation of undecalcified bone sections for auto and microradiography. Calc. Tiss. Res.10, 23–30 (1972).

    Article  CAS  Google Scholar 

  • Riggs, B. L., Jr., Bassingthwaighte, J. B., Jowsey, J., Pequegnat, E. P.: Autoradiographic method for quantitation of deposition and distribution of radiocalcium in bone. J. Lab. clin. Med.75, 520–528 (1970).

    PubMed  CAS  Google Scholar 

  • Wallgren, G.: Biophysical analyses of the formation and structure of human fetal bone. Acta paediat. Suppl.113 (1957).

Download references

Author information

Authors and Affiliations

  1. Bone Metabolism Research Unit, University Department of Medicine, Western Infirmary, W.1, Glasgow, UK

    C. M. McQueen &  D. A. Smith

  2. Regional Department of Clinical Physics and Bio-Engineering, Western Regional Hospital Board, Glasgow

    I. B. Monk & P. W. Horton

Authors
  1. C. M. McQueen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. D. A. Smith
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. I. B. Monk
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. P. W. Horton
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

McQueen, C.M., Smith, D.A., Monk, I.B. et al. A television scanning system for the measurement of the spatial variation of micro-density in bone sections. Calc. Tis Res. 11, 124–132 (1973). https://doi.org/10.1007/BF02547295

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02547295

Key words

Search

Navigation