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Serum apolipoproteins B and A-I and naturally occurring fatty liver in dairy cows

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Lipids

Abstract

Serum lipids and apolipoprotein (apo) B and A-I concentrations were determined in 164 dairy cows which had undergone liver biopsy in early lactation. The animals were divided into groups according to fatty liver severity on the basis of hepatic triglyceride content. The serum free fatty acid (FFA) concentration was higher in cows that developed fatty livers than in normal cows, and it correlated highly with liver triglycerides. Serum total cholesterol and triglyceride levels did not correlate with hepatic triglycerides. Both apo B and apo A-I levels were significantly decreased in fatty liver cows. In particular, apo B levels showed a strongly negative correlation with liver triglycerides. The present results suggest that hepatic apolipoprotein synthesis is impeded in fatty liver cows.

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Abbreviations

ANOVA:

analysis of variance

apo:

apolipoprotein

FFA:

free fatty acids

VLDL:

very low density lipoproteins

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Author notes

  1. Edgardo Marcos

    Present address: I.N.T.A., E.E.A. Rafaela, cc 22, 2300, Rafaela, Argentina

Authors and Affiliations

  1. Laboratoire des Maladies Metaboliques, Institut National de la Recherche Agronomique, Theix, 63 122, Ceyrat, France

    Edgardo Marcos, Andrzej Mazur, Philippe Cardot & Yves Rayssiguier

Authors
  1. Edgardo Marcos
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  2. Andrzej Mazur
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  3. Philippe Cardot
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  4. Yves Rayssiguier
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Marcos, E., Mazur, A., Cardot, P. et al. Serum apolipoproteins B and A-I and naturally occurring fatty liver in dairy cows. Lipids 25, 575–577 (1990). https://doi.org/10.1007/BF02537168

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  • DOI: https://doi.org/10.1007/BF02537168

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