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Comparison of cell membrane phospholipid fatty acids in five rat strains fed four test diets

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Lipids

Abstract

The fatty acid composition of phospholipids in peritoneal exudate cells and spleen cells was assessed in five rat strains fed four test diets of differing fatty acid composition. Distinctive patterns of fatty acids were seen in the total phospholipid preparations in both cell types in response to the diets which contained either olive, sunflower, linseed or fish oil. In general, similar fatty acid profiles were seen in each of the rat strains fed the same diet with the only evidence of possible genetic (strain) variation being a relative deficiency of Δ4 desaturase in Dark Agouti rats.

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Abbreviations

AA:

arachidonic acid

ALA:

α-linolenic acid

DGLA:

dihomoylinolenic acid

DHA:

docosahexaenoic acid

EPA:

eicosapentaenoic acid

GLC:

gas-liquid chromatography

LA:

linoleic acid

PBS:

phosphate buffered saline

TLC:

thin-layer chromatography

References

  1. Nelson, G.J., and Ackman, R.G. (1988)Lipids 23, 1005–1014.

    Article  PubMed  CAS  Google Scholar 

  2. McColl, S.R., Cleland, L.G., Whitehouse, M.W., and Vernon-Roberts, B. (1987)J. Rheumatol. 14, 197–201.

    PubMed  CAS  Google Scholar 

  3. Jeffery, F., and Redgrave, T.G. (1982)J. Lipid Res. 23, 154–160.

    PubMed  CAS  Google Scholar 

  4. Bligh, E.G., and Dyer, W.J. (1959)Can. J. Biochem. Physiol. 37, 911–917.

    PubMed  CAS  Google Scholar 

  5. Hays, W.L. (1973) inStatistics, pp. 418–421, Holt, Rinehart and Winston, Inc., New York.

    Google Scholar 

  6. Keys, A. (1970)Circulation 41, Suppl. 1, I, 1–211.

    Google Scholar 

  7. Simopoulos, A.P. (1986)J. Nutr. Growth Cancer 3, 69–81.

    CAS  Google Scholar 

  8. Lee, J.H., Sugano, M., and Ide, T. (1988)J. Nutr. Sci. Vitaminol 34, 117–129.

    PubMed  CAS  Google Scholar 

  9. Hwang, D.H., Boudreau, M., and Chanmugam, P. (1988)J. Nutr. 118, 427–437.

    PubMed  CAS  Google Scholar 

  10. Brenner, R.R. (1974)Molec. Cell. Biochem. 3, 41–52.

    Article  PubMed  CAS  Google Scholar 

  11. Garg, M.L., Sebokova, E., Thomson, A.B.R., and Clandinin, M.T. (1988)Biochem. J. 249, 351–356.

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Morialta Trust Bone and Joint Research Laboratory, Rheumatology Unit, Royal Adelaide Hospital, North Terrace, 5000, Adelaide, South Australia, Australia

    Leslie G. Cleland, Joanna S. Hawkes & Michael J. James

  2. Department of Paediatrics, Flinders Medical Centre, Bedford Park, South Australia, Australia

    Robert A. Gibson

Authors
  1. Leslie G. Cleland
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  2. Robert A. Gibson
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  3. Joanna S. Hawkes
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  4. Michael J. James
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Cleland, L.G., Gibson, R.A., Hawkes, J.S. et al. Comparison of cell membrane phospholipid fatty acids in five rat strains fed four test diets. Lipids 25, 559–564 (1990). https://doi.org/10.1007/BF02537165

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  • DOI: https://doi.org/10.1007/BF02537165

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