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Trans fatty acids. 1. Growth, fertility, organ weights and nerve histology and conduction velocity in sows and offspring

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Lipids

Abstract

Effects of dietarytrans fatty acids on the pre- and postnatal growth and development in pigs were studied with special emphasis on nervous tissue. In experiment 1, female pigs were fed partially hydrogenated fish oil (PHFO) (28%trans) or soybean oil (PHSBO) (36%trans), in comparison with lard (0%trans) from weaning (3 wk) through the first reproduction cycle (up to 2 yr). In experiment 2, female pigs were fed two fish oils (33 and 19%trans) in comparison with coconut oil (0%trans) in diets with low and high levels of linoleic acid (18∶2n−6cis,cis) from gestation until their offspring were three wk old. Compared with thetrans-free fats, thetrans-containing fats had no effect on growth and development, feed consumption and utilization or on the weight of the brain, heart, kidneys, liver, lungs or spleen in the adult sows and their offspring. No effects from the experimental fats were found on histology and conduction velocity of the peroneal nerve. An increased number of the sows fed PHFO had fertility problems compared with those fed lard and PHSBO in Expt. 1, but no similar effects were seen in Expt. 2. It is concluded that consumption oftrans fatty acids with 18–22 carbon atoms from PHFO and with 18 carbon atoms from PHSBO at levels that were 5 to 12 times higher than those normally consumed by humans had no detrimental effects on female pigs or their offspring during pregnancy and lactation.

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Abbreviations

CF:

short chain fatty acids

EFA:

essential fatty acids

FHFO:

“fully” hydrogenated fish oil/capelin oil

HFO:

hydrogenated fish oil

PHFO:

partially hydrogenated fish oil

PHSBO:

partially hydrogenated soybean oil

PHVO:

partially hydrogenated vegetable oil

PUFA:

polyunsaturated fatty acids

GLC:

gas liquid chromatograph

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Authors and Affiliations

  1. Norwegian Herring Oil and Meal Research Institute, N-5033, Fyllingsdalen, Bergen, Norway

    Johannes Opstvedt & Jan Pettersen

  2. Gades Institute, Department of Pathology, Haukeland Hospital, N-5016, Bergen, Norway

    Sverre J. Mork

Authors
  1. Johannes Opstvedt
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  2. Jan Pettersen
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  3. Sverre J. Mork
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Opstvedt, J., Pettersen, J. & Mork, S.J. Trans fatty acids. 1. Growth, fertility, organ weights and nerve histology and conduction velocity in sows and offspring. Lipids 23, 713–719 (1988). https://doi.org/10.1007/BF02535674

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  • DOI: https://doi.org/10.1007/BF02535674

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