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Interception of discrete oxygen species in aqueous media by cholesterol: Formation of cholesterol epoxides and secosterols

  • Symposium: Sterols Held at the AOCS Annual Meeting in New Orleans, LA, May 17–21, 1981
  • Published:
Lipids

Abstract

The oxidation products of cholesterol oxidized by different dioxygen species, hydroxyl radical, or triatomic species ozone variously implicated in biological oxidtions are compared. Some products are unique to the oxygen species involved, whereas others, such as the isomeric cholesterol 5,6-epoxides, are formed broadly by many oxygen species. The resolution of the isomeric cholesterol 5,6-epoxides by capillary column gas chromatography on SE-30 or SE-54 has been achieved.

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Author notes

  1. Jerzy Gumulka

    Present address: The Department of Chemistry, University of Warsaw, Warsaw, Poland

Authors and Affiliations

  1. Division of Biochemistry, University of Texas Medical Branch, 77550, Galveston, TX

    Jerzy Gumulka & Leland L. Smith

  2. Department of Gasteroenterology, University of Texas Health Science Center, 77030, Houston, TX

    Jan St. Pyrek

Authors
  1. Jerzy Gumulka
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  2. Jan St. Pyrek
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  3. Leland L. Smith
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Gumulka, J., Pyrek, J.S. & Smith, L.L. Interception of discrete oxygen species in aqueous media by cholesterol: Formation of cholesterol epoxides and secosterols. Lipids 17, 197–203 (1982). https://doi.org/10.1007/BF02535103

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  • DOI: https://doi.org/10.1007/BF02535103

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