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1-Docosanol and other long chain primary alcohols in developing rat brain

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Lipids

Abstract

Long chain alcohols were detected in developing rat brain at ages ranging from 5 to 40 days. They were at their highest level of 0.0109% of the total lipids at the age of 10 days and decreased to 0.0036% at the age of 40 days. They consisted mainly of hexadecanol, octadecanol, octadecenol, eicosanol, docosanol, and tetracosanol. The fact that substantial amounts of fatty alcohols having more than 20 carbon atoms were present in myelinating rat brain indicated a chain length specificity in their utilization for0-alkyl and0-alk-1-enyl glycerolipid biosynthesis.

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Authors and Affiliations

  1. The Hormel Institute, University of Minnesota, 55912, Austin, Minnesota

    V. Natarajan & H. O. O. Schmid

Authors
  1. V. Natarajan
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  2. H. O. O. Schmid
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Natarajan, V., Schmid, H.O.O. 1-Docosanol and other long chain primary alcohols in developing rat brain. Lipids 12, 128–130 (1977). https://doi.org/10.1007/BF02532985

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  • DOI: https://doi.org/10.1007/BF02532985

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