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The incorporation of14C-glycerol into different species of diglycerides and triglycerides in rat liver slices

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Lipids

Abstract

The relative rates of de novo synthesis of species of diglycerides and triglycerides from14C-glycerol were examined in rat liver slices. Diglycerides containing one or two double bonds per molecule and triglycerides containing four or more double bonds per molecule represented 70% and 60% respectively of the newly synthesized diglycerides and triglycerides. The newly synthesized triglycerides were more unsaturated than the endogenous triglycerides. Our results suggest that a nonrandom synthesis of species of diglycerides occurred followed by an almost random utilization of the various diglyceride species for the biosynthesis of triglycerides.

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Author notes

  1. Sister P. M. Slakey

    Present address: Saint Dominic College, 60174, Illinois, Saint Charles

Authors and Affiliations

  1. Department of Biological Chemistry, The University of Michigan, 48104, Ann Arbor, Michigan

    Edward E. Hill, William E. M. Lands & Sister P. M. Slakey

Authors
  1. Edward E. Hill
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  2. William E. M. Lands
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  3. Sister P. M. Slakey
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Hill, E.E., Lands, W.E.M. & Slakey, S.P.M. The incorporation of14C-glycerol into different species of diglycerides and triglycerides in rat liver slices. Lipids 3, 411–416 (1968). https://doi.org/10.1007/BF02531279

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  • DOI: https://doi.org/10.1007/BF02531279

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