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Expression of vimentin in cultured human keratinocytes is associated with cell—extracellular matrix junctions

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References

  1. Azumi N, Battifora H (1987) The distribution of vimentin and keratin in epithelial and nonepithelial neoplasms. A comprehensive immunohistochemical study on formalin-and alcoholfixed tumors. Am J Clin Pathol 88: 286–296

    PubMed  CAS  Google Scholar 

  2. Cheng J, Syder AJ, Yu QC, Letai A, Paller AS, Fuchs E (1992) The genetic basis of epidermolytic hyperkeratosis: a disorder of differentiation-specific epidermal keratin genes. Cell 70: 811–819

    Article  PubMed  CAS  Google Scholar 

  3. Chipev CC, Korge BP, Markova N, Bale SJ, DiGiovanna JJ, Compton JG, Steinert PM (1992) A leucine-proline mutation in the H1 subdomain of keratin 1 causes epidermolytic hyperkeratosis. Cell 70: 821–828

    Article  PubMed  CAS  Google Scholar 

  4. Chu Y-W, Runyan RB, Oshima RG, Hendrix MJC (1993) Expression of complete keratin filaments in mouse L cells augments cell migration and invasion. Proc Natl Acad Sci USA 90: 4261–4265

    Article  PubMed  CAS  Google Scholar 

  5. Coulombe PA, Hutton ME, Letai A, Hebert A, Paller AS, Fuchs E (1991) Point mutations in human keratin 14 genes of epidermolysis bullosa simplex patients: genetic and functional analyses. Cell 66: 1301–1311

    Article  PubMed  CAS  Google Scholar 

  6. Fuchs E (1990) Epidermal differentiation: the bare essentials. J Cell Biol 111: 2807–2814

    Article  PubMed  CAS  Google Scholar 

  7. Fuchs E (1994) Intermediate filaments and disease: mutations that cripple cell strength. J Cell Biol 125: 511–516

    Article  PubMed  CAS  Google Scholar 

  8. Fuchs E, Coulombe PA (1992) Of mice and men: genetic skin diseases of keratin. Cell 69: 899–902

    Article  PubMed  CAS  Google Scholar 

  9. Fuchs E, Weber K (1994) Intermediate filaments: structure, dynamics, function, and disease. Annu Rev Biochem 63: 345–382

    PubMed  CAS  Google Scholar 

  10. Garrod DR (1993) Desmosomes and hemidesmosomes. Curr Opin Cell Biol 5: 30–40

    Article  PubMed  CAS  Google Scholar 

  11. Georgatos SD, Marchesi VT (1985) The binding of vimentin to human erythrocyte membranes: a model system for the study of intermediate filament-membrane interactions. J Cell Biol 100: 1955–1961

    Article  PubMed  CAS  Google Scholar 

  12. Haake AR, Lane AT (1989) Retention of differentiated characteristics in human fetal keratinocytes in vitro. In Vitro 25: 592–600

    CAS  Google Scholar 

  13. Jones JCR, Goldman RD (1985) Intermediate filaments and the initiation of desmosome assembly. J Cell Biol 101: 506–517

    Article  PubMed  CAS  Google Scholar 

  14. Kouklis PD, Hutton E, Fuchs E (1994) Making a connection: direct binding between keratin intermediate filaments and desmosomal proteins. J Cell Biol 127: 1049–1060

    Article  PubMed  CAS  Google Scholar 

  15. McNutt MA, Bolen JW, Gown AM, Hammar SP, Vogel AM (1985) Coexpression of intermediate filaments in human epithelial neoplasms Ultrastruct Pathol 9: 31–43

    PubMed  CAS  Google Scholar 

  16. Nagle RB (1994) A review of intermediate filament biology and their use in pathologic diagnosis. Mol Biol Rep 19: 3–21

    Article  PubMed  CAS  Google Scholar 

  17. Pavalko FM, Otey CA (1994) Role of adhesion molecule cytoplasmic domains in mediating interactions with the cytoskeleton. Proc Soc Exp Biol Med 205: 282–293

    PubMed  CAS  Google Scholar 

  18. Pieper FR, van de Klundert FA, Raats JM, Henderik JB, Schaart G, Ramaekers FCS, Bloemendal H (1992), Regulation of vimentin expression in cultured epithelial cells. Eur J Biochem 210: 509–519

    Article  PubMed  CAS  Google Scholar 

  19. Richard MH, Viac J, Reano A, Gaucherand M, Thivolet J (1990) Vimentin expression in normal human keratinocytes grown in serum-free defined MCDB 153 medium. Arch Dermatol Res 282: 512–515

    Article  PubMed  CAS  Google Scholar 

  20. Schwarz MA, Owaribe K, Kartenbeck J, Franke WW (1990) Desmosomes and hemidesmosomes: constitutive molecular components. Annu Rev Cell Biol 6: 461–491

    Article  PubMed  CAS  Google Scholar 

  21. Shimizu T (1993) Presence and localization of proteins immunologically related to membrane skeletal proteins in human skin. Hokkaido J Med Sci 68: 42–53

    PubMed  CAS  Google Scholar 

  22. Spandau DF (1994) Distinct conformations of p53 are observed at different stages of keratinocyte differentiation. Oncogene 9: 1861–1868

    PubMed  CAS  Google Scholar 

  23. Stappenbeck TS, Bornslaeger EA, Corcoran CM, Luu HH, Virata ML, Green KJ (1993) Functional analysis of desmoplakin domains: specification of the interaction with keratin versus vimentin intermediate filament networks. J Cell Biol 123: 691–705

    Article  PubMed  CAS  Google Scholar 

  24. Steinert PM, Roop DR (1988) Molecular and cellular biology of intermediate filaments. Annu Rev Biochem 57: 593–625

    Article  PubMed  CAS  Google Scholar 

  25. Stewart M (1993) Intermediate filament structure and assembly. Curr Opin Cell Biol 5: 3–11

    Article  PubMed  CAS  Google Scholar 

  26. SundarRaj N, Rizzo JD, Anderson SC, Gesiotto JP (1992) Expression of vimentin by rabbit corneal epithelial cells during wound repair. Cell Tissue Res 267: 347–356

    Article  PubMed  CAS  Google Scholar 

  27. Takahashi, K, Folmer J, Coulombe PA (1994) Increased expression of keratin 16 causes anomalies in cytoarchitecture and keratinization in transgenic mouse skin. J Cell Biol 127: 505–520

    Article  PubMed  CAS  Google Scholar 

  28. Troyanovsky SM, Eshkind LG, Troyanovsky RB, Leube RE, Franke WW (1993) Contributions of cytoplasmic domains of desmosomal cadherins to desmosome assembly and intermediate filament anchorage. Cell 72: 561–574

    Article  PubMed  CAS  Google Scholar 

  29. Vikstrom KL, Lim S-S, Goldman RD, Borisy GG (1992) Steady state dynamics of intermediate filaments networks. J Cell Biol 118: 121–129

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Dermatology, Indiana School of Medicine, 46202, Indianapolis, Indiana, USA

    Diana Biddle

  2. Department of Biochemistry & Molecular Biology, Indiana University School of Medicine, Medical Research and Library Building, Room 349, 975 West Walnut Street, 46202, Indianapolis, Indiana, USA

    Dan F. Spandau

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  1. Diana Biddle
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  2. Dan F. Spandau
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Biddle, D., Spandau, D.F. Expression of vimentin in cultured human keratinocytes is associated with cell—extracellular matrix junctions. Arch Dermatol Res 288, 621–624 (1996). https://doi.org/10.1007/BF02505266

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  • DOI: https://doi.org/10.1007/BF02505266

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