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Relationship between the lipophilicity and specific hydrophobic surface area of some pesticides by RP-HPLC and HPTLC

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Summary

Using methanol-water mixtures as the mobile phases, the retention behaviors of thirty-seven pesticides were determined in RP-HPLC and RP-HPTLC. Regular retention behavior was observed for all the investigated pesticides: theirR m and logk values decreasing linearly with increasing concentration of methanol in the mobile phase. The lipophilicity and specific hydrophobic surface area values for each compound were obtained and they have a good linear relationship. Although the chemical structures of these pesticides were different, factor analysis proved that the lipophilicity and specific hydrophobic surface area of these compounds have much in common, and the insecticides, fungicides and herbicides could not be distinguished from each other according to their lipophilicity parameters obtained from chromatography method.

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Authors and Affiliations

  1. State Key Laboratory of Elemento-Organic Chemistry, Nankai University, 300071, Tianjin, P.R. China

    L. Zhang, M. Zhang, L. X. Wang & Q. S. Wang

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  1. L. Zhang
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  2. M. Zhang
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  3. L. X. Wang
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  4. Q. S. Wang
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Zhang, L., Zhang, M., Wang, L.X. et al. Relationship between the lipophilicity and specific hydrophobic surface area of some pesticides by RP-HPLC and HPTLC. Chromatographia 52, 305–308 (2000). https://doi.org/10.1007/BF02491022

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  • DOI: https://doi.org/10.1007/BF02491022

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