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Contrast harmonic ultrasound is a breakthrough technology in the diagnosis and treatment of hepatocellular carcinoma

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Conclusion

The noninvasive vascular technique of contrast-enhanced harmonic imaging is an extremely sensitive tool for detecting the intranodular blood flow in hepatic tumors. This method is drastically changing the diagnostic and therapeutic strategy of hepatic tumors, especially HCC, resulting in an eventual improvement in the prognosis of patients with HCC.

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Reference

  1. Matsui O, Kadoya M, Kameyama T, et al: Benign and malignant nodules in cirrhotic livers. Distinction based on blood supply.Radiology 1991;178: 493–497.

    PubMed  CAS  Google Scholar 

  2. Kudo M, Tomita S, Tochio H, et al: Small hepatocellular carcinoma: Diagnosis with US angiography with intraarterial CO2 microbubbles.Radiology 1992;182: 155–160.

    PubMed  CAS  Google Scholar 

  3. Kudo M, Tomita S, Tochio H, et al: Sonography with intraarterial infusion of carbon dioxide microbubbles (sonographic angiography): Value in differential diagnosis of hepatic tumors.AJR Am J Roentgenol 1992;158: 65–74.

    PubMed  CAS  Google Scholar 

  4. Kudo M, Tomita S, Tochio H, et al: Hepatic focal nodular hyperplasia: specific findings at dynamic contrast-enhanced ultrasonography with carbon dioxide microbubbles.Radiology 1991;179: 377–382.

    PubMed  CAS  Google Scholar 

  5. Kudo M: Imaging diagnosis of hepatocellular carcinoma and premalignant/borderline lesions.Semin Liver Dis 1999;19: 297–309.

    Article  PubMed  CAS  Google Scholar 

  6. Kudo M: Morphological diagnosis of hepatocellular carcinoma: Special emphasis on intranodular hemodynamic imaging.Hepatogastroenterology 1998;45L 1226–1231.

    PubMed  Google Scholar 

  7. Kudo M: Contrast-enhanced Harmonic Imaging of Hepatic Tumors. I-upgaku-shoin, Tokyo, 2001.

    Google Scholar 

  8. Hechemann RA, Cosgrove DO, Blomley MJK, et al: Liver lesions: Intermittent second-harmonic grayscale US can increase conspicuity with microbubble contrast material—Early experience.Radiology 2000;216: 592–596.

    Google Scholar 

  9. Ding H, Kudo M, Onda H, et al: Diagnosis of pancreatic islet cell tumor: Value of intermittent harmonic imaging.J Clin Ultrasound 2001;29: 411–416.

    Article  PubMed  CAS  Google Scholar 

  10. Ding H, Kudo M, Onda H, et al: Contrast-enhanced subtraction harmonic sonography for evaluating treatment response in patients with hepatocellular carcinoma.AJR Am J Roentgenol 2001;176: 661–666.

    PubMed  CAS  Google Scholar 

  11. Ding H, Kudo M, Onda H, et al: Hepatocellular carcinoma: Depiction of tumor parenchymal flow with intermittent harmonic power Doppler US during the early arterial phase in dual display mode.Radiology 2001;220: 349–356.

    PubMed  CAS  Google Scholar 

  12. Ding H, Kudo M, Maekawa K, et al: Detection of tumor parenchymal blood flow in hepatic tumors: value of second harmonic imaging with a galactose-based contrast agent.Hepatology Research 2001;21: 242–251.

    Article  PubMed  Google Scholar 

  13. William T, Forsberg SF: Ultrasonic characterization of the nonlinear properties of contrast microbubbles. Ultrasound Med 2000;26: 93–104.

    Article  Google Scholar 

  14. Kim TK, Choi BI, Han JK, et al: Hepatic tumors: Contrast agent-enhancement patterns with pulse-inversion harmonic US.Radiology 2000;216: 411–417.

    PubMed  CAS  Google Scholar 

  15. Ding H, Kudo M, Onda H, et al: Evaluation of posttreatment response of hepatocellular carcinoma with contrast-enhanced coded phase-inversion harmonic US: comparison with dynamic CT.Radiology 2001 (in press).

  16. Kudo M: Imaging blood flow characteristics of hepatocellular carcinoma.Oncology 2001;61: 48–56.

    Google Scholar 

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Kudo, M. Contrast harmonic ultrasound is a breakthrough technology in the diagnosis and treatment of hepatocellular carcinoma. J Med Ultrasonics 28, 79–81 (2001). https://doi.org/10.1007/BF02481273

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  • DOI: https://doi.org/10.1007/BF02481273

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