Abstract
The first case of a ventrally exophytic pontine glioma with extensive and dense calcification is reported. A 10-year-old boy presented with a generalized seizure. The skull radiogram and CT scan showed a dense area of calcification, revealed by MRI as the core of a ventrally exophytic tumor. The pathologic diagnosis was fibrillary astrocytoma.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Stroink AR, Hoffman HJ, Hendrick EB, et al (1987) Transependymal benign dorsally exophytic brain stem gliomas in childhood: diagnosis and treatment recommendations. Neurosurgery 20:439–444
Suga T, Uchida K, Kagawa S, et al (1995) A surgically treated case of ventrally exophytic pontine glioma. Neurol Surg 23:1037–1042
Hoshi M, Yoshida K, Shimazaki K, et al (1997) Correlation between MIB-1 staining indices and recurrence in low-grade astrocytomas. Brain Tumor Pathol 14:47–51
Dierssen G, Figolls J, Trigueros F, et al (1984) A pontine astrocytoma with radiological evidence of very extensive and dense calcification. Case report. Neurochirurgia (Stuttg) 27:190–192
Duffner PK, Klein DM, Cohen ME (1978) Calcification in brainstem gliomas. Neurology 28:832–834
Takeuchi K, Yokota H, Konishi Y, et al (1982) A pontine glioblastoma-like tumour associated with a chondrosarcoma. Acta Neurochir (Wien) 64:243–251
Okuchi K, Hiramatsu K, Morimoto T, et al (1992) Astrocytoma with widespread calcification along axonal fibers. Neuroradiology 34:328–330
Tanaka Y, Takeuchi K, Maeda T (1975) Calcification in glioma: first report with special reference to roentgenological calcification. Neurol Surg 3:219–225
Epstein F (1985) A staging system for brain stem gliomas. Cancer 56:1804–1806
Halpin S, Kingsley D (1993) Disappearance of cerebral calcification as a sign of tumor growth. AJNR Am J Neuroradiol 14:119–122
Hui M, Tenenbaum HC (1998) New face of an old enzyme: alkaline phosphatase may contribute to human tissue aging by inducing tissue hardening and calcification. Anat Rec 253:91–94
Shuto T, Ohtsubo Y, Sekido K, et al (1996) Rapidly growing calcified cerebellar astrocytoma in infants. Child Nerv Syst 12:107–109
Tanaka M, Shibui S, Nomura K, et al (2000) Malignant intracerebral nerve sheath tumor with intratumoral calcification. Case report. J Neurosurg 92:338–341
Tashiro Y, Kondo A, Aoyama I, et al (1990) Calcified metastatic brain tumor. Neurosurgery 26:1065–1070
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Niimi, M., Yoshida, K., Mayanagi, K. et al. Extensive and dense calcification in the core of a ventrally exophytic brainstem glioma. Brain Tumor Pathol 19, 101–103 (2002). https://doi.org/10.1007/BF02478935
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02478935