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A neural circuit which exhibits some features of epileptic attacks

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Abstract

A neural model based on a generalization of a model proposed in 1938 in the first edition of the author'sMathematical Biophysics (Chicago: Univ. of Chicago Press) is described. It possesses the property that due to some endogenous or exogenous stimulus, which may be of random nature, a pathway may suddenly begin to fire spontaneously. This spontaneous firing may either gradually spread over other pathways and eventually cease, or it may remain localized within one or a few pathways and then cease. Which of the two types of events occurs depends on the values of a number of parameters. The case of spreading reminds one of Jacksonian epilepsy.

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Rashevsky, N. A neural circuit which exhibits some features of epileptic attacks. Bulletin of Mathematical Biophysics 34, 71–78 (1972). https://doi.org/10.1007/BF02477026

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  • DOI: https://doi.org/10.1007/BF02477026

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