Abstract
An ACTH-producing thymic carcinoid tumour was diagnosed in a 10-year-old girl, 8 years after bilateral adrenalectomy for Cushing’s syndrome. The peptides produced by the tumour were characterised thoroughly. High circulating levels of β-endorphin and other peptides may have contributed to mood and behaviour disturbances.
References
Hale AC, Besser GM, Rees LH (1986) Characterisation of proopiomelanocortin-derived peptides in pituitary and ectopic adrenocorticotrophin-secreting tumours. J Endocrinol 1:49–56
Pullan PT, Clement-Jones V, Corder R, Lowry PJ, Besser GM, Rees LH (1980) ACTH, LPH and related peptides in the ectopic ACTH syndrome. Clin Endocrinol 13:437–445
Pullan PT, Clement-Jones V, Corder R, Rees GM, Rees LH, Besser GM, Macedo MM, Galvao-Teles A (1980) Ectopic production of methionine enkephalin and beta-endorphin. Br Med J 280:758–759
Salyer WR, Salyer DC, Eggleston JC (1976) Carcinoid tumours of the thymus. Cancer 37:958–973
Wick MR, Carney JA, Bernatz PE, Brown LR (1982) Primary mediastinal carcinoid tumours. Am J Surg Pathol 6:195–205
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
McCaughey, E.S., Walker, V., Rolles, C.J. et al. Actopic ACTH production by a thymic carcinoid tumour. Eur J Pediatr 146, 590–591 (1987). https://doi.org/10.1007/BF02467360
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02467360