Skip to main content
Log in

Stochastic theory of compartments: One and two compartment systems

  • Published:
Bulletin of Mathematical Biology Aims and scope Submit manuscript

Abstract

Previous work on compartmental systems is generalized (i) to allow the particles present at time zero to have a different lifetime distribution than those which arrive after time zero, and (ii) to allow a particle which enters the system at timet to have a lifetime distribution which is a function oft but is otherwise quite general. The one and two compartment models are analyzed under the above conditions and compared to previous results of Thakuret al. (1974), Purdue (1974) and Cardenas and Matis (1974). Finally, some results for the two compartment, reversible system are given. The analysis used is a blend of direct random variable and queueing theoretic techniques.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Literature

  • Bartholomay, A. F. 1958. “Stochastic Models for Chemical Reactions: I. Theory of the Unimolecular Reaction Process.”Bull. Math. Biophysics,20, 176–190.

    Google Scholar 

  • Cardenas, M. and J. H. Matis. 1974. “On the Stochastic Theory of Compartments: Solution ofn-Compartment Systems with Irreversible, Time Dependent Transition Probabilities.”Bull. Math. Biology,36, 489–504.

    MATH  MathSciNet  Google Scholar 

  • Matis, J. H. and H. O. Hartley. 1971. “Stochastic Compartmental Analysis: Model and Least Squares Estimation from Time Series Data.”Biometrics,27, 77–102.

    Article  Google Scholar 

  • Mirasol, N. M. 1963. “The Output of anM|G| ∞ Queueing System is Poisson.”Ops. Res.,11, 282–284.

    Article  MATH  Google Scholar 

  • Purdue, P. 1974. “Stochastic Theory of Compartments.”Bull. Math. Biology,36, 305–309.

    MATH  MathSciNet  Google Scholar 

  • Thakur, A. K., A. Rescigno and D. E. Schafer. “On the Stochastic Theory of Compartments: I. A Single Compartment System.”Bull. Math. Biophysics,34, 53–63.

  • —— and —. 1974. “On the Stochastic Theory of Compartments: II. Multi-Compartment Systems.”Bull. Math. Biology,35, 263–271.

    Article  MathSciNet  Google Scholar 

  • Takács, L. 1962.Introduction to the Theory of Queues. New York: Oxford University Press.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Purdue, P. Stochastic theory of compartments: One and two compartment systems. Bltn Mathcal Biology 36, 577–587 (1974). https://doi.org/10.1007/BF02463269

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02463269

Keywords

Navigation