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Colocalization of neurotransmitters in presynaptic boutons of inhibitory synapses in the lamprey spinal cord

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Abstract

Electron-microscopic immunocytochemical studies were performed to detect GABA and glycine immunoreactivity in presynaptic axon terminals in the central gray matter of the spinal cord of the lampreyLampetra fluviatilis. The immunopositive presynaptic terminals contacting identified dendrites of motoneurons and unidentified postsynaptic profiles included terminals immunopositive for GABA only (44%) and glycine only (26%), as well as terminals containing GABA and glycine (30%). Glycine-immunopositive presynaptic terminals contained flattened synaptic vesicles. Large synaptic vesicles with dense cores were present along with classical synaptic vesicles in 74% of GABA-immunopositive boutons.

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Authors and Affiliations

  1. I. M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of sciences, 44 M. Torez Prospekt, 194223, St. Petersburg, Russia

    N. P. Veselkin & V. O. Adamina

  2. INSERM U-106 Laboratory for Neuromorphology, Development, and Evolution, Paris, France

    J. -P. Rio

  3. National Museum of Natural History, Paris, France

    J. -P. Rio & J. Repérant

Authors
  1. N. P. Veselkin
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  2. V. O. Adamina
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  3. J. -P. Rio
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  4. J. Repérant
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Translated from Rossiiskii Fiziologicheskii Zhurnal imeni I. M. Sechenova, Vol. 85, No. 4, pp. 515–522, April, 1999.

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Veselkin, N.P., Adamina, V.O., Rio, J.P. et al. Colocalization of neurotransmitters in presynaptic boutons of inhibitory synapses in the lamprey spinal cord. Neurosci Behav Physiol 30, 547–552 (2000). https://doi.org/10.1007/BF02462613

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  • DOI: https://doi.org/10.1007/BF02462613

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