Abstract
Genetic polymorphisms of six blood groups and seven biochemical genetic markers were investigated in six Iranian populations (Turks, Kurds, Lurs, Zabolis, Baluchis and Zoroastrians). Eight of the genetic systems (ABO, MNSs, Kidd, C3, AP, AK, PGM1 and EsD) showed conclusive heterogeneity among these populations. Comparison of gene frequencies with the few available samples of Iranian populations demonstrated an intra-ethnic and extensive overall genetic diversity in the Iranian plateau. A gradient of C3*F gene was also discernible within the geographical region of Iran which may reflect the relics of the historical movements of different racial groups in this region. The present genetic variation may reflect the differences in the structure of these populations, the analysis of which is further attempted in the accompanying paper.
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Literature cited
Akbari M.T., Papiha S.S., Roberts D.F. and Farhud D.D., 1984.Serogenetic investigations of two populations of Iran. Hum. Hered. 34: 371–377.
Akbari M.T., Papiha S.S., Roberts D.F. and Farhud D.D., 1986a.Genetic differentiation among Iranian Christian communities. Amer. J. Hum. Genet. 38: 84–98.
Akbari M.T., Papiha S.S. and Roberts D.F., 1986b.Population genetics of the Persians and other peoples in Iran. Z. Morph. Anthrop. 76: 197–217.
Bajatzadeh M. and Walter H., 1969.Investigations on the distribution of blood and serum groups in Iran. Hum. Biol. 41: 401–415.
Boue A. and Boue J., 1956.Etude sur la repartition des groupes sanguins en Iran II. Ann. Inst. Pasteur 91: 898–911.
Bowman J.E., 1964.Haptoglobin and transferrin differences in some Iranian populations. Nature (Lond.) 201: 88.
Farhud D.D., Amirshahi P. and Hedayat Sh., 1978.The distribution of haptoglobin types in Bandar-Abbass (S. of Iran). Iranian J. Publ. Health 7(4): 215.
Farhud D.D., Ananthakrishnan R., Walter H. and Loser J., 1973.Electrophoretic investigations of some red cell enzymes in Iran. Hum. Hered. 23: 263–266.
Farhud D.D. and Walter H. 1972.Hp subtypes in Iranians. Hum. Hered. 22: 184–189.
Farhud D.D. and Walter H. 1973.Polymorphism of C'3 in German, Bulgarian, Iranian and Angolan populations. Humangenetik 17: 161–164.
Godber M.J., Kopec A.C., Mourant A.E., Tills D. and Lehmann E.E., 1973.Biological studies of Yemenite and Kurdish Jews in Israel and other groups in South-West Asia. IX. The hereditary blood factors of the Yemenite and Kurdish Jews. Phil. Trans. s.B. 266: 169–184.
Harris H. & Hopkinson D.A., 1976.Handbook of Enzyme Electrophoresis in Human Genetics. North-Holland.
Kirk R.L., Keats B., Blake N.M., McDermid E.M., Ala F., Karimi M., Nickbin B., Shabazi H. and Kmet J., 1977.Genes and people in the Caspian littoral: a population genetic study in Northern Iran. Amer. J. Phys. Anthrop. 46: 377–390.
Lehmann H., Ala F., Hedeyat S., Montazaemi K., Kavini Nejad H., Lightman S., Kopec A.C., Mourant A.E., Teesdale P. and Tills D., 1973.The hereditary blood factors of the Kurds of Iran. Phil. Trans. Roy. Soc. Lond., Series B, 266: 195–206 (1973).
Nijenhuis L.E., 1964.Blood group frequencies in Iran. Vox Sang. 9: 723–740.
Papiha S.S., Seyedna Y. and Sunderland E., 1982.Phosphoglucomutase (PGM) and group-specific component (Gc) isoelectric focusing among Zoroasterians of Iran. Ann. Hum. Biol. 9: 571–574.
Papiha S.S., White I., Akbari M.T. and Farhud D.D., 1985.Isoelectric focusing of Vitamin D binding protein (Cc): Genetic diversity in the population of Iran. Jap. J. Hum. Genet. 30: 69–73.
Sawhney K.S., 1975.Genetic polymorphisms in selected populations in south west and south Asia. Ph.D. thesis. University of Durham, U.K.
Seyedna Y., Sunderland E., Woolley V. and Smith M.T., 1984.A blood group investigation of the Zoroastrians of Iran. Coll. Anthropol. 8: 31–39.
Smithies O., 1955.Grouped variations in the occurrence of new protein components in normal human serum. Nature 175: 307–308.
Sunderland E. and Smith H.M., 1966.The blood groups of the Shi'a in Yazd, Central Iran. Hum. Biol. 38: 50–59.
Tabatabai H., 1977.A comparative genetical investigation of the Iranian Armenians and Jews. M.Sc. thesis. University of Tehran, Iran.
Teisberg P., 1970.High voltage agarose gel electrophoresis in the study of C3 polymorphism. Vox Sang. 19: 47–56.
Tills D., Warlow A., Mourant A.E., Kopec A.C., Edholm O.G. and Garradr G., 1977.The blood groups and other hereditary blood factors of Yemenite and Kurdish Jews. Ann. Hum. Biol. 4(3): 259–274.
Walter H. and Bajatzadeh M. 1968.Studies on the distribution of the human red cell acid phosphatase polymorphism in Iranians and other populations. Acta Genetica, Basel 18: 421–428.
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Amirshahi, P., Sunderland, E., Farhud, D.D. et al. Population genetics of the peoples of Iran I. Genetic polymorphisms of blood groups, serum proteins and red cell enzymes. Int. J. Anthropol. 7, 1–10 (1992). https://doi.org/10.1007/BF02447604
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DOI: https://doi.org/10.1007/BF02447604