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Serotonin insufficiency of neutrophils

  • Experimental Methods for Clinical Practice
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The mobility of neutrophils is found to be depressed by serotonin antagonists (toxins and drugs) in patients with wound infection. Addition of serotonin eliminates serotonin insufficiency of neutrophils, which is expressed in acceleration of their mobility. Data are presented showing that serotonin is indispensable for maintaining neutrophil and platelet homeostasis.

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Authors and Affiliations

  1. A. V. Vishnevskii Institute of Surgery, Russian Academy of Medical Sciences, Moscow

    A. P. Simonenkov, V. D. Fedorov & A. A. Galkin

Authors
  1. A. P. Simonenkov
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  2. V. D. Fedorov
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  3. A. A. Galkin
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Translated frombyulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 121, No. 4, pp. 467–469, April, 1996

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Simonenkov, A.P., Fedorov, V.D. & Galkin, A.A. Serotonin insufficiency of neutrophils. Bull Exp Biol Med 121, 426–427 (1996). https://doi.org/10.1007/BF02446749

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  • DOI: https://doi.org/10.1007/BF02446749

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