Abstract
In rabbits under nembutal anesthesia delta sleep-inducing peptide injected intravenously or directly into a ventricle of the brain raised the threshold for ventricular fibrillation. Its effect on the electrical stability of the heart after central administration developed later than after systemic administration. Bilateral vagotomy did not alter the central effects of this peptide.
Similar content being viewed by others
References
M. I. Arkhangel'skaya and M. A. Zvyagintseva,Pat. Fiziol., No 2, 45–49 (1989).
V. I. Badikov, R. A. Burchuladze, A. E. Gabuniya,et al., Fiziol. Zh.,71, No 7, 840–847 (1986).
V. M. Koval'zon, in:Recent Developments in Science and Technology. Human and Animal Physiology Series [in Russian], Vol. 31, Moscow (1986), pp. 3–58.
E. V. Koplik, D. F. Vedvaev, I. I. Mikhaleva,et al., Dokl. Akad. Nauk SSSR,267, No 1, 230–233 (1982).
F. Z. Meerson, N. A. Abdikaliev, V. I. Kuznetsov,et al., Kardiologiya,30, No 8, 69–72 (1990).
K. V. Sudakov,Fiziol. Zh., No 3, 1–13 (1991).
L. S. Ul'yaninskiiFiziol. Zh., No 10, 1273–1279 (1990).
L. S. Ul'yaninskii, M. I. Arkhangel'skaya, M. A. Zvyagintseva,et al., in:Proceedings of the Research Council on Experimental and Applied Physiology, Russian Academy of Medical Sciences, Vol. 1, (1992), pp. 86–102.
W. A. Banks and A. J. Kastin,Life Sci.,41, 1319–1338 (1987).
A. Bjartell, in:Delta Sleep-Inducing Peptide: A Mammalian Regulatory Peptide, London (1990), pp. 11–67.
M. V. Graf and A. J. Kastin,Peptides,7, 1165–1187, (1986).
J. Han,Amer. J. Cardiol.,24, No 6, 857–864 (1969).
B. Lown, in:First USA-USSR Joint Symposium on Sudden Death (Proceedings), Washington (1978), pp. 387–404.
M. Monnier and G.A. Schoenenberger, in:Sleep (ed. by W.P. Koella and P. Levin), Basel (1977), pp. 256–263.
S. Raeissi and K.L. Audus,J. Pharm. Pharmacol.,41, No 12, 848–852 (1989).
J.E. Skinner, in:Stress and Heart Disease, ed. by R.E. Beamish, Boston (1985), pp. 44–59.
R.L. Verrier and B. Lown,Circulation,62, No 4, 176–183 (1980).
Author information
Authors and Affiliations
Additional information
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, No 6, pp. 566–568, June, 1994
Rights and permissions
About this article
Cite this article
Arkhangel'skaya, M.I. Central and peripheral actions of delta sleep-inducing peptide on electrical stability of the heart. Bull Exp Biol Med 117, 565–567 (1994). https://doi.org/10.1007/BF02444319
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02444319