Skip to main content
SpringerLink
Log in

Ceramic implant materials

  • Biomaterials Supplement
  • Published:
Medical and Biological Engineering and Computing Aims and scope Submit manuscript

Abstracts

Historically ceramics are the oldest man-made non-animal-based materials. The use of metals began some thousand of years later and plastics have only become available during the last century. In contrast to this sequence of events, systematic and detailed evaluation of the applicability of ceramics for use in artificial organs or as bone and joint replacements did not start before the 1960s; while metals and plastics had already been in use for several decades. The research work on ceramics soon revealed surprising properties: some ceramics have been shown to be biocompatible in a particular way and tribologically favourable, a surprising type of bonding between some glass-ceramics and bone tissue was, discovered. Biodegradable types of calciumphosphate open the possibilities for temporary implants which need not be removed by a second operation, and there are ceramics which obviously can be used in the cardiovascular system.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Aragon, P. J. andHulbert, S. F. (1972) Corrosion of Ti-6A1-4V in simulated body fluids and bovine plasma.J. Biomed. Mater.,6, 155–164.

    Article  Google Scholar 

  • Bhaskar, S. N., Brady, J. M., Getter, L., Grower, M. F. andDriskell, T. D. (1971) Biodegradable ceramic implants in bone.Oral Surg.,32, 336.

    Article  Google Scholar 

  • Blencke, B. A., Pfeil, E. andBrömer, H. (1974) Rasterelektronenmikroskopische Untersuchungen der Reaktion des Knochens auf glaskeramische Implantate.Z. Orthop.,112, 978–980.

    Google Scholar 

  • Blencke, B. A., Brömer, H. andDeutscher, K. (1975) Glaskeramik — ein neuer, bioaktiver Implantatwekstoff.Med. Orthop. Technik,95, 144–148.

    Google Scholar 

  • Blencke, B. A., Deutscher, K. andBrömer, H. (1980) Struktur und Eigenschaften des Implantatlagers bioaktiver Glaskeramik. Paper presented at the second Münchner symposium für experimentelle Orthopädie, München 15–16th Feb. 1980 (in press).

  • Bokros, J. C., Gott, V. L., LaGrange, L. D., Fadali, A. M., andRamos, M. D. (1970) Heparin sorptivity and blood compatibility of carbon surfaces.J. Biomed. Mater. Res.,4, 145–187.

    Article  Google Scholar 

  • Boutin, P. (1972) Arthroplastie totale de la hanche par prothèse en alumine frittée.Revue de chirurgie orthopédique et réparatrice de l'appareil moteur (Paris),58, 229–246.

    Google Scholar 

  • Brömer, H. andDeutscher, K. (1978) Verbund bioaktiver Glaskeramik mit metallischem Prothesenwerkstoff. Paper Dt. Glastechn. Ges. Würzburg.

  • Büsing, C. M., Heimke, G., Schulte, W. andLinn, W. (1979) Gibt es ein Lastschattenphänomen? Biomechanische Aspekte bei Zahnimplantaten aus Al2O3-Keramik.Der Pathologe,1, 61.

    Google Scholar 

  • Cameron, H. U., MacNab, I., andPilliar, R. M. (1977) Evaluation of a biodegradable ceramic.J. Biomed. Mater. Res.,11, 179–186.

    Article  Google Scholar 

  • Denissen, H. J., van Dijk, H. J. andde Groot, K. (1978) Dental root implants of sintered tricalciumphosphate. Paper no. 22, Meeting European Society of Biomaterials, Brussels, 22nd–23rd March.

  • Driskell, T. D., O'Hara, M. J. andSheets, Jr., H. D. (1972) Development of ceramic and ceramic composite devices for maxillofacial applications.J. Biomed. Mater. Res. Symposium,2, 345–361.

    Article  Google Scholar 

  • Dunn, E. J. andWhite, E. W. (1976) Bone ingrowth in replamineform porous implants. In Williams, D. (Ed.)Biocompatibility of implant materials, Sector Publishing Ltd., London, 80–84.

    Google Scholar 

  • Ebert, R. andSchaldach, M. (1979) The applicability of rutile ceramics for cardiovascular devices. Paper presented at the 12th International Conference on Medical and Biological Engineering, fifth International Conference on Medical Physics, Jerusalem, Israel.

  • Eulenberger, J. andNiederer, P. G. (1978) Correlation of histology and interfacial shear strength of bioactive and bioinert implant materials. Transactions 4th Annual Meeting of the Society for Biomaterials, San Antonio, Texas, 141–142.

  • Eulenberger, J., Stich, H., andNiederer, P. G. (1978) Biokeramik im Rattenversuch (vorläufige Mitteilung).Schweiz. Mschr. Zahnheilk.,88, Nr. 4.

    Google Scholar 

  • Gourley, I. M. G. andArnold, J. P. (1960) The experimental replacement of segmental defects in bone with a plaster of Paris-epoxy resin mixture.Am. J. Veterinary Res. 1119.

  • Greenspan, D. C. andHench, L. L. (1977) Chemical and mechanical behaviour of bioglass-coated, alumina.J. Biomed. Mater. Res.,11, 503–509.

    Article  Google Scholar 

  • Griss, P. (1978) Al2O3-ceramics versus bio-glass versus silicium-nitride. Paper Bio-Ceramics Symposium Keele University, UK, 16th September, to be published.

  • Griss, P. andHeimke, G. (1976) Discussion remarks. InWilliams D. (Ed.)Biocompatibility of implant materials, Sector Publishing Ltd., London, 68–69.

    Google Scholar 

  • Griss, P., von Andrian-Werburg, H., Krempien, B. andHeimke, G. (1973) Biological activity and histocompatibility of dense Al2O3/MgO ceramic implants in rats.J. Biomed. Mater. Res. Symposium,4, 453–462.

    Article  Google Scholar 

  • Griss, P., Krempien, B., von Andrian-Werburg, H., Heimke, G., andFleiner, R. (1973) Experimentelle Untersuchung zur Gewebeverträglichkeit oxidkeramischer (Al2O3) Abriebteilchen.Arch. orthop. Unfall-Chir.,76, 270–279.

    Article  Google Scholar 

  • Griss, P., Krempien, B., von Andrian-Werburg, H., Heimke, G., Fleiner, R. andDiehm, Th. (1974) Experimental analysis of ceramic tissue interactions: a morphologic, fluorescence-optic, and radiographic study on dense alumina oxide ceramic in various animals.J. Biomed. Mater. Res. Symposium,5, 39–48.

    Article  Google Scholar 

  • Griss, P., Heimke, G., von Andrian-Werburg, H., Krempien, B., Reipa, S., Lauterbach, H. J. andHartung, H. J. (1975) Morphological and bio mechanical aspects of Al2O3 ceramic joint replacement: experimental results and design considerations for human endoprostheses.J. Biomed. Mater. Res. Symposium,6, 177–188.

    Article  Google Scholar 

  • Griss, P., Heimke, G. andvon Andrian-Werburg, H., (1975) Die Aluminiumoxidkeramik-Metal-Verbundprothese: elne neue Hüftgelenktotalendoprothese zur teilweise zementfreien Implantation.Arch. orthop. Unfall-Chir.,81, 259–266.

    Article  Google Scholar 

  • Griss, P., Heimke, G., Krempien, B., Hartung, H. J., Reipa, S., Lauterbach, H. J. andDiehm, Th. (1976) Experimental ceramic joint replacement. In Williams, D. (Ed.)Biocompatibility of Implant Materials, Sector Publishing Ltd., London, 70–79.

    Google Scholar 

  • Griss, P., Silber, R., Merkle, B. andHaehner, K. (1976) Biomechanically induced tissue reacations after Al2O3-ceramic hip joint replacement: experimental and early clinical results.J. Biomed. Mater. Res. Symposium,7, 519–528.

    Article  Google Scholar 

  • Griss, P., Greenspan, D. C., Heimke, G., Krempien, B., Buchinger, R., Hench, L. L. andJentschura, G. (1976) Evaluation of a bioglass-coated Al2O3 total hip prosthesis in sheep.J. Biomed. Mater. Res. Symposium,7, 511–518.

    Article  Google Scholar 

  • Griss, P., Werner, E., Buchinger, R., Büsing, C. M. andHeimke, G. (1977) Zur Frage der unspezifischen Sarkomentstehung um Al2O3-keramische Implantate.Arch. orthop. Unfall-Chir.,90, 29–40.

    Article  Google Scholar 

  • Griss, P., Werner, E., Heimke, G., Raute-Kreinsen, U. (1978) Vergleichende experimentelle Untersuchungen an Al2O3-Keramik und mit mod. Bioglas (L. L. Hench) beschichteter Al2O3-Keramik. II Ergebnisse mit belasteten Implantaten.Arch. Orthop. Traumat. Surg.,92, 199–210.

    Article  Google Scholar 

  • Gross, U. andStrunz, V. (1978) Development and structure of bone and bone marrow after implantation of glas ceramic ceravital. Transactions of 4th Annual Meeting of the Society for Biomaterials, San Antonio, Texas, 46.

  • Harms, J. andMäusle, E. (1979) Tissue reaction to ceramic implant material.J. Biomed. Mater. Res.,13, 67–87.

    Article  Google Scholar 

  • Haubold, A. (1977) Carbon in prosthetics.Annals New York Academy of Sciences,283, 383–395.

    Google Scholar 

  • Hayek, E. andNewesely, H. (1963) Pentacalcium monohydroxyorthophosphate (hydroxylapatite).Inorganic Syntheses Series,7, 63–65.

    Google Scholar 

  • Heimke, G. (1978) Enossale Implantate aus Aluminiumoxidkeramik: über die Tätigkeit einer von der Landesregierung Baden-Württemberg geförerten Arbeitsgruppe.Dtsch. zahnärztl. Z.,33, 306–310.

    Google Scholar 

  • Heimke, G., Griss, P. andKrempien, B. (1975) Eine Hüftgelenktotalendoprothese zur teilweise zementfreien Implantation.Medizinalmarkt/Acta Medicotechnica,23, 243–247.

    Google Scholar 

  • Heimke, G., Griss, P., Jentschura, G., Krempien, B., Gugel, E., Petzenhauser, I. andHennicke, H. W. (1977) Keramische und keramik beschichtete Knochenersatzwerkstoffe.Forschungsberichte des Bundesministers für Forschung und Technologie, BMFT-FBT 77-70.

  • Heimke, G., Griss, P., Jentschura, G. andWerner, E. (1978) Die Aussage histologischer befunde zur Beurteilung von Knochenersatzwerkstoffen.Arch. Orthop. Traumat. Surg.,91, 267–276.

    Article  Google Scholar 

  • Heimke, G. andPolack, F. M. (1977) Keramische Keratoprothesen. InJaeger, W. (Ed.) Kunstoffimplantate in der Opthalmologie,Bergmann, J.F., Verlag, München, 28–35.

    Google Scholar 

  • Hench, L. L., Splinter, R. J., Allen, W. C. andGreenlee, T. K. (1971) Bonding mechanisms at the interface of ceramic prosthetic materials.J. Biomed. Mater. Res. Symposium,2, 117–141.

    Article  Google Scholar 

  • Hench, L. L., Greenlee, T., Allen, W. C. andPiotrowski, G. (1970) An investigation of bonding mechanisms at the interface of a prosthetic material. US Army Medical Research and Development Command, contract DADA 17-70-C-001, report1, bis 6 (1975).

  • Hentrich, R. L., Graves, G. A., Stein, H. G. andBaipal, P. K. (1971) An evaluation of inert and resorbable ceramics for future clinical orthopaedic applications.J. Biomed. Mater. Res.,5, 25.

    Article  Google Scholar 

  • Hoffman, F. Private communication 1979.

  • Hoffman, F., Harnisch, J. P., Strunz, V., Bunte, M., Gross, U. M., Männer, K., Brömer, H. andDeutscher, K. (1978) Osteo-Keramo-Keratoprothese: eine Modifikation der osteo-odonto-keratoprothese nach Strampelli.Klin. Mbl. Augenheilk.,173, 747–755.

    Google Scholar 

  • Hulbert, S. F., Young, F. A., Mathews, R. S., Klawitter, J. J., Talbert, C. D. andStelling, F. H. (1970) Potential of ceramic materials as permanently implantable skeletal prostheses.J. Biomed. Mater. Res.,4, 433–456.

    Article  Google Scholar 

  • Hulbert, S. F., King, Jr., F. M., Klawitter, J. J. (1971) Initial surface interaction of blood and blood components with Al2O3.J. Biomed. Mater. Res. Symposium,2, 69–89.

    Article  Google Scholar 

  • Hulbert, S. F., Klawitter, J. J. andBowman, L. S. (1972) History of ceramic orthopaedic implants.Mat. Res. Bull.,7, 1239–1246.

    Article  Google Scholar 

  • Hulbert, S. F., Morrison, S. J. andKlawitter, J. J. (1972) Tissue reaction to three ceramics of porous and nonporous structures.J. Biomed. Mater. Res.,6, 347–374.

    Article  Google Scholar 

  • Jahnke, K., Plester, D. andHeimke, G. (1979) Aluminiumoxid-Keramik, ein bioinertes Material für die Mittelohrchirurgie.Arch. Ohren-, Nasen- und Kehlkopfheilkunde,223, 373–376.

    Google Scholar 

  • Jenkins, G. M. andGrigson, G. J. (1979) The fabrication of artifacts out of glassy carbon and carbon-fiber-reinforced carbon for biomedical applications.J. Biomed. Mater. Res.,13, 371–394.

    Article  Google Scholar 

  • Karbe, K., Köster, K., Kramer, H., Heide, H., Kling, G. andKönig, R. (1975) Knochenwachstum in porösen keramischen Implantaten beim Hund.Langenbecks Arch. Chir.,338, 109–116.

    Article  Google Scholar 

  • Kawahara, H. (1969) Biological consideration of ceramics.Dent. Eng. (Japan),9, 28–31.

    Google Scholar 

  • Klawitter, J. J. andHulbert, S. F. (1971) Application of porous ceramics for the attachment of load bearing internal orthopedic applications.J. Biomed. Mater. Res. Symposium,2, 161–229.

    Article  Google Scholar 

  • Köster, K., Heide, H. andKönig, R. (1977) Resorbierbare Calciumphosphatkeramik im Tierexperiment unter Belastung.Langenbecks Arch. Chir.,343, 173–181.

    Article  Google Scholar 

  • Köster, K., Heide, H. andKönig, R. (1977) Histologische Untersuchungen an der Grenzfläche zwischen Knowchengewebe und Calciumphosphat-, Calciumaluminat- und Aluminiumoxidkeramik.Z. Orthop.,115, 693–699.

    Google Scholar 

  • Krempien, B., Schulte, W., Kleineikenscheidt, H., Lindner, K., Schareyka, R. andHeimke, G. (1978) Lichtoptische und rasterelektronenmikroskopische Untersuchungen an der Grenzfläche von Implantaten aus Aluminiumoxid-Keramik im Unterkieferknochen von hunden.Dtsch. zahnärztl. Z.,33, 332–340.

    Google Scholar 

  • Kristen, K., Krempien, B., Schulz, P., Singer, R., Wörle, M. andHeimke, G. (1978) Der Einfluss der Form von Aluminiumoxid-Keramik-Implantaten auf die Verweildauer im Unterkiefer des Hundes.Dtsch. zahnärztl. Z.,33, 311–318.

    Google Scholar 

  • Levin, M. P., Getter, L., Cutright, D. E. andBhaskar, S. N. (1974) Biodegradable ceramic in periodontal defects.Oral Surg.,38, 344–351.

    Article  Google Scholar 

  • Mittelmeier, H. (1975) Implantatwekstoffe in der Orthopädie.Med. Orthop. Technik,6, 152.

    Google Scholar 

  • Mountvala, A. J. (1973) Surface properties of bioceramic vascular prostheses.Ceramic Bulletin,52, 479–482.

    Google Scholar 

  • Moyle, D. D., Klawitter, J. J. andHulbert, S. F. (1973) Mechanical properties of the bone-porous biomaterial interface: elastic behavior.J. Biomed. Mater. Res. Symposium,4, 363–382.

    Article  Google Scholar 

  • Mühlbradt, L. (1978) Neurophysiologische Methoden und Untersuchungen zu Rezeptorfunktionen an Implantaten.Dtsch. zahnärztl. Z.,33, 363–364.

    Google Scholar 

  • Polack, F. M. andHench, L. L. (1975) Progress report, National Institute of General Medical Sciences (GM-21056), National Institutes of Health.

  • Polack, F. M. andHeimke, G. (1979) Keratoprothesen aus korundeinkristall und-keramik. Paper presented at the Conference of the German Ophthalmological Society, Heidelberg (in print).

  • Predecki, P., Stephan, J. E., Auslaender, B. A., Mooney, Vert. L. andKirkland, K. (1972) Kinetics of bone growth into cylindrical channels in aluminum oxide and titanium.J. Biomed. Mater. Res.,6, 375–400.

    Article  Google Scholar 

  • Rejda, B. V. (1977) Composite materials for hard tissue replacement. Academisch Proefschrift (PhD thesis) Vrije Universiteit Te Amsterdam, Amsterdam.

    Google Scholar 

  • Rock, M. (1933) Künstliche Ersatzteile für das Innere und Aussere des menschlichen und tierischen Körpers. German Patent 583589.

  • Salzer, M., Zweymüller, K., Locke, H., Plenk, Jr., H. andPunzet, G. (1975) Biokeramische Endoprothesen.Medizinisch-Orthopädische Technik,95, 40–45.

    Google Scholar 

  • Sandhaus, S. (1967) Bone implants and drills and taps for bone surgery. British Patent 1083769.

  • Schareyka, R. (1979) Die Sulcus-Fluid-Fliessrate (SFFR) bei Tübinger Sofortimplantaten aus Aluminiumoxidkeramik.Dtsch. zahnärttl. Z.,33, 360–362.

    Google Scholar 

  • Schulte, W. andHeimke, G. (1976) Das Tübinger Sofortimplantat.Die Quintessenz,6, 17–23.

    Google Scholar 

  • Schulte, W., Kleineikenscheidt, H., Schareyka, R. andHeimke, G. (1978) Konzept und Prüfung des Tübinger Sofortimplantates.Dtsch. zahnärztl. Z.,33, 319–325.

    Google Scholar 

  • Schulte, W., Kleineikenscheidt, H., Lindner, K. andSchareyka, R. (1978) Das Tübinger Sofortimplantat in der klinischen Prüfung.Dtsch. zahnärztl. Z.,33, 348–359.

    Google Scholar 

  • Schulte, W., Kleineikenscheidt, H., Lindner, K., Schareyka, R., Heimke, G., Gerlach, Ch. andHardegg, W. (1978) Tierexperimente zur Frage der Einheilung des Tübinger Sorfortimplantates.Dtsch. zahnärztl Z.,33, 326–331.

    Google Scholar 

  • Smith, L. (1963) Ceramic-plastic material as a bone substitute.Arch. Surg.,87, 653.

    Google Scholar 

  • Solar, R. J., Pollack, S. R. andKorostoff, E. (1979) In vitro corrosion testing of titanium surgical implant alloys: an approach to understanding titanium release from implants.J. Biomed. Mater. Res.,13, 217–250.

    Article  Google Scholar 

  • Strampelli, B. (1970) Osteo-odonto-keratoprosthesis.Ann. Ottal. Clin. Ocul., 1–29.

  • Strunz, V., Bunte, M., Stellmach, R., Gross, U. M., Kühl, K., Brömer, H. andDeutscher, K. (1977) Bio aktive Glaskeramik als Implantatmaterial in der Kieferchirurgie.Dtsch. zahnärztl. Z.,32, 287–290.

    Google Scholar 

  • Strunz, V., Bunte, M., Gross, U. M., Hoffman, F., Harnisch, J. P., Männer, K., Brömer, H. andDeutscher, K. (1977) Keratoprothese aud Glaskeramik AusKunstostoffe in der Ophthalmologie.Jaeger, W. (Ed.),Bergmann, J.F. Verlag, München, 197–200.

    Google Scholar 

  • Strunz, V., Bunte, M., Gross, U. M., Männer, K., Brömer, H. andDeutscher, K. (1978) Beschichtung von metallimplantaten mit bioaktiver Glaskeramik Ceravital.Dtsch. zahnärztl. Z.,33 862–865.

    Google Scholar 

  • Swart, J. G. N., Feenstra, L., Ponssen, H., andDe Groot, K. (1979) Voorlopige klinische ervaringen met een botvervangingsmateriaal, gesinterd tricalciumfosfaat.Ned. T. Geneesk.,123.

  • Willert, H. G., Semlitsch, M., Buchhorn, G. andKriete, U. (1978) Materialverschleiss und Gewebereaktionen bei künstlichen Gelenken.Orthopäde,7, 62.

    Google Scholar 

  • Wullstein, S. R. (1979) Keramik und Humankleber beim Aufbau der Tympanoplastik.Arch. Ohren-, Nasen- und Kehlkopfheilkunde,223, 373.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Friedrichsfeld GmBH, Steinzeug- und Kunststoffwerke, D-6800, Mannheim 71

    G. Heimke

  2. Orthopädische Klinik Lindenhof, Fakultät für klinische Medizin der Universität Heidelberg, D-6800, Mannheim 1

    P. Griss

Authors
  1. G. Heimke
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. Griss
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Heimke, G., Griss, P. Ceramic implant materials. Med. Biol. Eng. Comput. 18, 503–510 (1980). https://doi.org/10.1007/BF02443328

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02443328

Keywords

Search

Navigation