Abstract
Methods to measure microvascular blood flow usually probe small volumes of tissue. Therefore, spatial differences in skin blood flow alter the signal, when the sensing element is moved a short distance. To reduce the effects of spatial differences in skin blood flow, but yet record its temporal variability, a new integrating probe for laser Doppler flowmeters was developed. The probe receives light from seven different scattering volumes simultaneously, and the instrument processes an integrated signal which is ultimately taken as the average flow value. Significant spatial integration is found, as spatial variability is reduced by the square root of the number of scattering volumes.
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Salerud, E.G., Nilsson, G.E. Integrating probe for tissue laser Doppler flowmeters. Med. Biol. Eng. Comput. 24, 415–419 (1986). https://doi.org/10.1007/BF02442697
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DOI: https://doi.org/10.1007/BF02442697