Abstract
A simple model of the beat-to-beat properties of the cardiovascular system is used to interpret the results of spectral analysis of blood-pressure and interval data. The model consists of two equations, one representing the fast regulation of interval by the systolic pressure (baroreflex), the other one representing a Windkessel approximation of the systemic arterial system. The model, when applied to interval and blood-pressure data from resting subjects, explains the lack of respiratory variability in the diastolic pressure values. The baroreflex equation seems to describe the data only in the region of respiratory frequencies. The shape of the phase spectrum of systolic pressures against intervals is modelled by difference equations, but no physiological interpretation of these equations is given.
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Arndt, J. O., Morgenstern, J. andSamodelev, L. (1977) The physiologically relevant information regarding systemic blood pressure encoded in the carotid sinus baroreceptor discharge pattern.J. Physiol., (London),268, 775–791.
de Boer, R. W., Karemaker, J. M. andStrackee, J. (1983) Beatto-beat variability of heart interval and blood pressure.Automedica,4, 217–222.
de Boer, R. W., Karemaker, J. M. andStrackee, J. (1985) Relationships between short-term blood-pressure fluctuations and heart-rate variability in resting subjects I: a spectral analysis approach.Med. & Biol. Eng. & Comput.,23, 352–358.
Jenkins, G. M. andWatts, D. G. (1968)Spectral analysis and its applications. Holden-Day, San Francisco.
Jury, E. I. (1973)Theory and application of the z-transform method. Robert E. Krieger Publishing Co., Huntington, New York.
Levy, M. N. andMartin, P. J. (1979) Neural control of the heart. InHandbook of physiology, section 2: The cardiovascular system, vol. 1: the heart.Berne, R. M., Sperelakis, N. andGeiger, S. R. (Eds.), American Physiological Society, Bethesda, MD, 581–620.
Pickering, T. G., Gribbin, B., Strange Petersen, E., Cunningham, D. J. C. andSleight, P. (1972) Effects of autonomic blockade on the baroreflex in man at rest and during exercise.Circ. Res.,30, 177–185.
Scher, A. M. andYoung, A. G. (1970) Reflex control of heart rate in the unanesthetized dog.Am. J. Physiol.,218, 780–789.
Simon, A. C., Safar, M. E., Levenson, J. A., London, G. M., Levy, B. I. andChau, N. P. (1979) An evaluation of large arteries compliance in man.,237, H550-H554.
Sleight, P. (1980) The physiology of heart-rate control by arterial baroreceptors in man and animals. InThe study of heart-rate variability.Kitney, R. I. andRompelman, O. (Eds.), Clarendon Press, Oxford, 107–116.
Smyth, H. S., Sleight, P. andPickering, G. W. (1969) Reflex regulation of arterial pressure during sleep in man: a quantitative method of assessing baroreflex sensitivity.Circ. Res.,24, 109–121.
Watt, T. B. andBurrus, C. S. (1976) Arterial pressure contour analysis for estimating human vascular properties.J. Appl. Physiol.,40, 171–176.
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de Boer, R.W., Karemaker, J.M. & Strackee, J. Relationships between short-term blood-pressure fluctuations and heart-rate variability in resting subjects II: a simple model. Med. Biol. Eng. Comput. 23, 359–364 (1985). https://doi.org/10.1007/BF02441590
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DOI: https://doi.org/10.1007/BF02441590