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Stimulation of nonspecific resistance in mice by β-heptylglycoside muramyl dipeptide

  • Microbiology and Immunology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The ability of β-heptylglycoside muramyl dipeptide (glymuride) to stimulate nonspecific resistance in mice is studied. Glymuride prevents the death of up to 80% animals intraperitoneally infected withSalmonella typhi in a dose of 100 LD50. Glymuride is effective in both oral and intravenous administration. The ED50 for these routes of administration are calculated.

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References

  1. I. P. Ashmarin and A. A. Vorob'ev,Statistical Methods and Microbiological Studies [in Russian], Leningrad (1962).

  2. A. E. Zemlyakov and V. Ya. Chirva,Khimiya Prirod. Soedinen., No. 5, 714–718 (1987).

    Google Scholar 

  3. O. V. Kalyuzhin,Zh. Mikrobiol., No. 1, 104–108 (1998).

    Google Scholar 

  4. O. V. Kalyuzhin and B. B. Fuks,Byull. Eksp. Biol. Med.,122, No. 12, 658–661 (1996).

    CAS  Google Scholar 

  5. O. V. Kalyuzhin, B. B. Fuks, N. V. Bovin,et al.,—Ibid.,117, No. 5, 510–513 (1994).

    Article  CAS  Google Scholar 

  6. B. F. Pinegin, T. M. Andronova, and M. I. Karsonova,Int. J. Immunorehabilitation, No. 6, 27–34 (1997).

    Google Scholar 

  7. O. V. Kalyuzhin, A. E. Zemlyakov, and B. B. Fuchs,Int. J. Immunopharmacol.,18, No. 11, 651–659 (1996).

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. M. Mechnikov Institute of Vaccines and Sera, Russian Academy of Medical Sciences, Moscow

    O. V. Kalyuzhin, V. V. Kalyuzhin, A. E. Zemlyakov, S. I. Elkina, M. V. Shkalev & V. V. Sergeev

  2. Institute of Human Morphology, Russian Academy of Medical Sciences, Moscow

    O. V. Kalyuzhin, V. V. Kalyuzhin, A. E. Zemlyakov, S. I. Elkina, M. V. Shkalev & V. V. Sergeev

  3. Kristal-Med, Moscow

    O. V. Kalyuzhin, V. V. Kalyuzhin, A. E. Zemlyakov, S. I. Elkina, M. V. Shkalev & V. V. Sergeev

Authors
  1. O. V. Kalyuzhin
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  2. V. V. Kalyuzhin
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  3. A. E. Zemlyakov
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  4. S. I. Elkina
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  5. M. V. Shkalev
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  6. V. V. Sergeev
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 127, No. 5, pp. 543–545, May, 1999

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Kalyuzhin, O.V., Kalyuzhin, V.V., Zemlyakov, A.E. et al. Stimulation of nonspecific resistance in mice by β-heptylglycoside muramyl dipeptide. Bull Exp Biol Med 127, 489–490 (1999). https://doi.org/10.1007/BF02434948

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  • DOI: https://doi.org/10.1007/BF02434948

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