Abstract
Proliferative and degenerative variants of structural and functional changes in the cell populations of renal glomeruli are revealed. These variants differ in the intensity of biosynthetic reactions in endotheliocytes, mesangiocytes, and parietal epitheliocytes. The degenerative variant is characterized by inhibition of RNA and DNA synthesis and ultrastructural alterations in endotheliocytes, which attests to the leading role of damage to glomerular endothelial associations in destruction of renal glomeruli.
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S. Yu. Bogomazova, O. P. Gladskikh, A. A. Ivanov,et al., Arkh. Patol., No. 6, 45–50 (1997).
M. S. Ignatova, E. A. Kharina, V. A. Spitsyn,et al., Ter. Arkh.,69, No. 6, 44–49 (1997).
A. Coen and S. Nast,Nefrologiya,2, No. 3, 117–139 (1998).
G. I. Nepomnyashchikh,Frontier Tissues (Mucosa and Skin) in Morphogenesis of General Pathology [in Russian], Novosibirsk (1996).
L. M. Nepomnyashchikh, G. I. Nepomnyashchikh, S. V. Aidagulova,et al., Pathomorphology of Glomerular and Tubulointerstitial Nephrites and Nephropathies [in Russian], Novosibirsk (1997).
L. M. Nepomnyashchikh, L. D. Sidorova, G. I. Nepomnyashchikh,et al., Byull. Sib. Otdeleniya Ross. Akad. Med. Nauk, No. 1, 123–129 (1996).
N. A. Mukhin, I. M. Balkarov, A. N. Britov,et al., Ter. Arkh.,69, No. 6, 5–10 (1997).
M. A. Pal'tsev and A. A. Ivanov,Arkh. Patol., No. 6, 13–16 (1994).
Yu. L. Perov and V. I. Fedorov, ——Ibid., No. 3, 3–10 (1980).
D. S. Sarkisov, A. A. Pal'tsyn, and B. V. Vtyurin,Electron Microscopic Radioautography of the Cell [in Russian], Moscow (1980).
V. V. Serov, in:Inflammation [in Russian], Eds. V. V. Serov and V. S. Paukov, Moscow (1995), pp. 518–540.
A. V. Cybulsky, D. J. Stewart, and M. I. Cybulsky, J. Am. Soc. Nephrol.,3, No. 7, 1398–1404 (1993).
M. Nagata, Y. Akioka, Y. Tsunoda,et al., Kidney Int.,48, No. 2, 527–535 (1995).
M. Rachman and M. C. Smith,JAMA Rossiya,2, No. 4, 46–57 (1999).
J. M. Rebibou, C. J. He, F. Delarue,et al., Nephrol. Dial. Transplant.,7, No. 4, 288–292 (1992).
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 11, pp. 591–596, November, 1999
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Nepomnyashchikh, L.M., Nepomnyashchikh, G.I., Aidagulova, S.V. et al. Ultrastructural and biosynthetic reactions in cell populations of renal glomeruli of the kidney under conditions of glomerular pathology. Bull Exp Biol Med 128, 1174–1178 (1999). https://doi.org/10.1007/BF02433431
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DOI: https://doi.org/10.1007/BF02433431