Abstract
Esophageal webs and rings may have a congenital origin and have been associated with iron-deficiency states and esophageal mucosal inflammation. Cutaneous diseases associated with esophageal webs and rings include benign mucosal pemphigoid and epidermolysis bullosa dystrophica. We report three cases of patients with psoriasis and associated single or multiple esophageal webs. Two of the three patients experienced a significant degree of dysphagia requiring periodic esophageal dilatation. Esophageal abnormalities did not seem to correlate directly with the extent or activity of psoriasis. The cause of esophageal webs or rings in these patients with psoriasis is not known. This report suggests, but does not prove, that there may be an association between these conditions.
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References
Enterline H, Thompson J: Congenital defects, rings, and webs. In Enterline H, Thompson J (eds):Pathology of the Esophagus. New York: Springer-Verlag, 1984, pp 23–41
Shamma'a MH, Benedict EB: Esophageal webs: a report of 58 cases and an attempt at classification.N Engl J Med 259:378–384, 1985
Hillemeir C, Toloukian R, McCallum R, Giziboski J: A previously unrecognized complication of epidermolysis bullosa.Pediatrics 67:678–682, 1981
Baden HP, Pugliese L: Psoriasis. In Dowling HF (ed):Disease A Month. Chicago: Year Book Medical Publishing, 1973, pp. 3–47
Sidi E, Zagula-Maly ZW, Hincky M:Psoriasis. Springfield, IL: Charles C. Thomas, 1968, pp 3–29
Paterson DR: A clinical type of dysphagia.J Laryngol Rhin Otol 34:289–291, 1919
Kelly AB: Spasm at entrance to oesophagus.J Laryngol Rhin Otol 34:285–289, 1919
Lindegard B: Diseases associated with psoriasis in a general population of 159,200 middle-aged urban, native Swedes.Dermatologica 172:298–304, 1986
Curtis DJ, Cruess DF: Pharyngoesophageal swallowing: a review of 618 video recorded cases.Military Med 149:545–549, 1984
Ekberg O: Cineradiography in normal and abnormal pharyngo-esophageal deglutition. Skurup, Sweden:Lidbergs Blankett AB, 1981, pp 173–184
Nosher JL, Campbell WL, Seamon WB: The clinical significance of cervical esophageal and hypopharyngeal webs.Radiology 117:45–47, 1975
Weaver JW, Kaude JV, Hamlin BJ: Webs of the lower esophagus: a complication of gastroesophageal reflux?AJR 142:289–292, 1984
Forber EM, Nall L, Streffing A: Psoriasis: A disease of the total skin.J Am Acad Dermatol 12:150–156, 1985
Weinstein GD, Frost P: Abnormal cell proliferation in psoriasis.J Invest Derm 50:254–259, 1968
Saiag P, Coulomb B, Lebreton C, Belle E, Dubertretk: Psoriatic fibroblasts induce hyperproliferation of normal keratinocytes in a skin equivalent model in vitro.Science 230:669–672, 1985
MacLaughlin JA, Gange W, Taylor D, Smith E, Holic MF: Cultured psoriatic fibroblasts from involved and uninvolved sites have a partial but not absolute resistance to the proliferation-inhibition activity of 1.25-dihydroxyvitamine D3.Proc Natl Acad Sci 82:5409–5412, 1985
Hendel L, Larsen JK, Ammitzbøll, Asboe-Hansen G: A study of cell proliferation kinetics in the small intestinal epithelium of psoriasis patients.Clin Expt Dermatol 9:329–335, 1984
Dupre A, Christol B, Lassere J: Geographic lip: a variant of geographic tongue.Cutis 17:263–265, 1976
Weathers DR, Baker G, Archard HO: Psoriasiform lesions of the oral mucosa.Oral Surg 37:872–888, 1974
Kren O: Die psoriasis vulgaris der mundschleim-haut.Arch Derm Syph (Berlin) 166–511, 1932