Abstract
Primary leiomyosarcoma of the thyroid gland is extremely rare, and to the best of our knowledge only five well-documented cases have been reported in the world literature. We herein report a 58-year-old female patient with primary leiomyosarcoma of the thyroid who was successfully treated by total thyroidectomy with a modified neck dissection. Immunohistochemically, the tumor cells showed positive reactivity to α-smooth muscle actin and vimentin. Radical surgery was thus considered to be essential in the treatment of this rare but rather aggressive malignancy.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Adachi M, Wellmann KF, Garcia R (1969) Metastatic leiomyosarcoma in brain and heart. J Pathol 98:294–296
Chetty R, Clark SP, Dowling JP (1993) Leiomyosarcoma of the thyroid: Immunohistochemical and ultrastructural study. Pathology 25:203–205
Iida Y, Katoh R, Yoshioka M, Oyama T, Kawaoi A (1993) Primary leiomyosarcoma of the thyroid gland. Acta Pathol Jpn 43:71–75
Kawaguchi Y, Kanazawa M, Nakayama K, Urazumi K, Takeuchi S, Abe R (1990) A case of leiomyosarcoma of the thyroid gland showing fatal outcome with rapid course (in Japanese with English abstract). Nihon Rinshou Gekai Gakkai Zasshi (Jpn J Clin Surg) 51:1217–1221
Kawahara E, Nakanishi I, Terahata S, Ikegaki S (1988) Leiomyosarcoma of the thyroid gland. A case report with a comparative study of five cases of anaplastic carcinoma. Cancer 62:2558–2563
Thomas MA, Fine G (1960) Leiomyosarcoma of veins. Report of 2 cases and review of the literature. Cancer 13:96–101
Carcangiu ML, Steeper T, Zampi G, Rosai J (1985) Anaplastic thyroid carcinoma: A study of 70 cases. Am J Clin Pathol 83:135–138
LiVolsi VA, Brooks JJ, Arendash-Durand B (1987) Anaplastic thyroid tumors: Immunohistology. Am J Clin Pathol 87:434–442
Aldinger KA, Samaan NA, Ibanez M, Hill Jr CS (1987) Anaplastic carcinoma of the thyroid: A review of 84 cases of spindle and giant cell carcinoma of the thyroid. Cancer 41:2267–2275
Nishiyama RH, Dunn EL, Thompson NW (1972) Anaplastic spindle-cell and giant-cell tumors of the thyroid gland. Cancer 30:113–127
Graham H, Daniel C (1984) Ultrastructure of an anaplastic carcinoma of the thyroid. Am J Clin Pathol 61:690–696
Jao W, Gould VE (1975) Ultrastructure of anaplastic (spindle and giant cell) carcinoma of the thyroid. Cancer 35:1280–1292
Andrion A, Bellis D, Delsedime L, Bussolati G, Mazzucco G (1988) Leiomyoma and neurilemona: Report of two unusual non-epithelial tumours of the thyroid gland. Virchows Arch [A] 413:367–372
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Ozaki, O., Sugino, K., Mimura, T. et al. Primary leiomyosarcoma of the thyroid gland. Surg Today 27, 177–180 (1997). https://doi.org/10.1007/BF02385912
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF02385912