Summary
The aim of the present report was to compare the current patterns of incidence and prevalence of end-stage renal failure and mode of renal replacement therapy in patients with Type 1 (insulin-dependent) and Type 2 (non-insulin-dependent) diabetes mellitus in Europe. All Type 1 and Type 2 diabetic patients recorded on the Registry of the European Dialysis and Transplant Association as being alive on renal replacement therapy were analysed according to age, sex, geographic distribution, and mode of therapy (haemodialysis, peritoneal dialysis or renal transplantation). During 1990 3981 diabetic patients commenced renal replacement therapy in Europe, and at 31 December 1990 a total of 15, 197 diabetic patients were receiving treatment. One-third were reported to be Type 2 diabetic patients, but the true proportion is expected to be higher. Both male and female Type 2 diabetic patients were older than Type 1 patients. Major geographic variations were observed; annual acceptance of Type 2 diabetic patients for treatment was greatest in Austria (10.7 per million) and equal to Type 1 patients, whereas the number of Type 1 diabetic patients was four times that of Type 2 patients in Sweden, Finland and Norway. Overall, the majority of Type 2 diabetic patients (80%) were treated by haemodialysis, 14% by peritoneal dialysis, and 6% had a functioning renal transplant. However, transplantation was the preferred option in young patients (48% of 25–34 year olds) and in Sweden and Norway (45% of all Type 2 patients).
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References
Viberti GC, Walker JD (1992) Pathogenesis of diabetic nephropathy. In: AEG Raine (ed) Advanced renal medicine. Oxford University Press, Oxford, pp 83–91
Joint Working Party on Diabetic Renal Failure of the BDA, the Renal Association and the Research Unit of the Royal College of Physicians (1988) Renal failure in diabetes in the UK: deficient provision of care in 1985. Diabetic Med 5: 79–84
Brunner FP, Giesecke B, Gurland HJ et al. (1976) Combined report on regular dialysis and transplantation in Europe. Proc Eur Dial Transp Assoc 12: 2–64
Brunner FP, Brynger H, Challah S et al. (1988) Renal replacement therapy in patients with diabetic nephropathy, 1980–85. Nephrol Dial Transplant 3: 585–595
Held PJ, Port FK, Blagg CR, Agodoa LYC (1990) United States Renal Data System 1990 annual report. Am J Kid Dis [Suppl 2]: 1–106
Jarrett RJ (1991) The epidemiology of diabetes mellitus. In: Pickup J, Williams G (eds) Textbook of diabetes, vol 1. Blackwell Scientific Publications, Oxford, pp 47–56
Geerlings W, Tufveson G, Brunner FP et al. (1991) Combined report on regular dialysis and transplantation in Europe, XXI, 1990. Nephrol Dial Transplant 6 [Suppl 4]: 5–28
World Bank Atlas (1990) The World Bank, Washington DC
Raine AEG, Margreiter R, Brunner FP et al. (1992) Report on management of renal failure in Europe XXII, 1992. Nephrol Dial Transplant 7: [Suppl 2]: 7–35
Catalano C, Postorino M, Kelly PJ et al. (1990) Diabetes mellitus and renal replacement therapy in Italy: prevalence, main characteristics and complications. Nephrol Dial Transplant 5: 788–796
Stephen SGW, Gillaspy JA, Clyne D, Mejia A, Pollok VE (1990) Racial differences in the incidence of end stage renal disease in type I and II diabetes mellitus. Am J Kid Dis 15: 562–567
Cowie CC, Port FK, Wolfe RA, Savage PJ, Moll PP, Hawthorne VM (1989) Disparities in incidence of diabetic end-stage renal disease according to race and type of diabetes. N Eng J Med 321: 1074–1079
Hasslacher C, Ritz E, Wahl P, Michael C (1989) Similar risks of nephropathy in patients with type I and type II diabetes mellitus. Nephrol Dial Transplant 4: 859–863
Fassbinder W, Brunner FP, Brynger H et al. (1989) Combined report on regular dialysis and transplantation in Europe, XX. Nephrol Dial Transplant 6: [Suppl 1] 5–35
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On behalf of the European Dialysis and Transplant Association Registry
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Raine, A.E.G. Epidemiology, development and treatment of end-stage renal failure in Type 2 (non-insulin-dependent) diabetic patients in Europe. Diabetologia 36, 1099–1104 (1993). https://doi.org/10.1007/BF02374505
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DOI: https://doi.org/10.1007/BF02374505