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Cardiotonic activities of 3,5-seco-4-nor-cardenolides inRana nigromaculata

  • Specialia Pharmacologica
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Zusammenfassung

Die cardiotonische Aktivität von 4 neuen, aus Digitoxigenin hergestellten 3,5-Seco-4-norcardenoliden auf das isolierte Froschherz wurde geprüft. Die Ergebnisse zeigen, dass für die positive inotrope Wirkung eines Cardenolids das intakte Steroidgerüst nicht notwendig ist.

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Literatur

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  8. This study was supported by a Grant-in-Aid from Tokyo Biochemical Research Foundation.

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Author notes

  1. H. Tsuru, N. Ishikawa & T. Shigei

    Present address: Department of Pharmacology, Nagoya University School of Medicine, Tsurumai-cho, Showa-ku, 466, Nagoya, (Japan)

  2. T. Anjyo & M. Okada

    Present address: Tokyo Biochemical Research Institute, Takada, Toshima-ku, 171, Tokyo, (Japan)

Authors and Affiliations

  1. Department of Pharmacology, Nagoya University School of Medicine, Tsurumai-cho, Showa-ku, 466, Nagoya, (Japan)

    T. Anjyo & M. Okada

  2. Tokyo Biochemical Research Institute, Takada, Toshima-ku, 171, Tokyo, (Japan)

    H. Tsuru, N. Ishikawa & T. Shigei

Authors
  1. H. Tsuru
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  2. N. Ishikawa
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  3. T. Shigei
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  4. T. Anjyo
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  5. M. Okada
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Tsuru, H., Ishikawa, N., Shigei, T. et al. Cardiotonic activities of 3,5-seco-4-nor-cardenolides inRana nigromaculata . Experientia 31, 955–956 (1975). https://doi.org/10.1007/BF02358874

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  • DOI: https://doi.org/10.1007/BF02358874

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