Summary
Acetazolamide and ouabain, metabolic inhibitors which interfere with certain membrane transport systems, reduce the rate of water elimination by maleGlossina morsitans morsitans. The results suggest that water is transported across membranes during diuresis and that a ouabain sensitive Na+K+ ATPase and an acetazolamide-sensitive carbonic anhydrase are involved in diuresis.
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Literatur
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I thank MissM. I. Buick for her assistance in maintaining the tsetse colony, Mr.B. M. Rolseth for his assistance in this experiment and Dr.D. A. Craig and Dr.B. K. Mitchell for their comments on the manuscript. This work was financed (in part) by a grant (No. 6801-51) from the Defence Research Board of Canada.
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Gooding, R.H. Inhibition of diuresis in the tsetse fly (Glossina morsitans) by ouabain and acetazolamide. Experientia 31, 938–939 (1975). https://doi.org/10.1007/BF02358863
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DOI: https://doi.org/10.1007/BF02358863